Evidence map›Paper›PMID 35241316›Full record

ArticleAnais brasileiros de dermatologia

Sensitizing agents found in children and adolescents with recalcitrant atopic dermatitis: a cross-sectional study with a pediatric battery.

Cristiane Almeida Soares Cattani, Kenselyn Oppermann, Simone Perazzoli, Nathalia Hoffmann Guarda, Paula Baréa, Renan Rangel Bonamigo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Anais brasileiros de dermatologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 11 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Cristiane Almeida Soares CattaniSanitary Dermatology Outpatient Clinic, Secretaria da Saúde do Estado do Rio Grande do Sul, Porto Alegre, RS, Brazil; Postgraduate Program in Pathology, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS, Brazil. Electronic address: crisalmeidacattani@gmail.com.
Kenselyn OppermannSanitary Dermatology Outpatient Clinic, Secretaria da Saúde do Estado do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Simone PerazzoliSanitary Dermatology Outpatient Clinic, Secretaria da Saúde do Estado do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Nathalia Hoffmann GuardaSanitary Dermatology Outpatient Clinic, Secretaria da Saúde do Estado do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Paula BaréaSanitary Dermatology Outpatient Clinic, Secretaria da Saúde do Estado do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Renan Rangel BonamigoPostgraduate Program in Pathology, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS, Brazil; Faculty of Medicine, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Secretaria da Saúde · BRUniversidade Federal de Ciências da Saúde de Porto Alegre · BRUniversidade Federal do Rio Grande do Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAtopic dermatitis is the most common inflammatory skin disease in childhood and has an important impact on quality of life, especially severe cases or those that are recalcitrant to treatments. Sensitization to allergens with the potential for allergic contact dermatitis is a factor associated with cases of recalcitrant atopic dermatitis. Understanding the relationship between atopic dermatitis, allergens, and allergic contact dermatitis is essential. In Brazil, there are no studies on sensitization to allergens found in patch tests with pediatric batteries in patients with atopic dermatitis.

objectivesTo verify the main sensitizing agents, the prevalence of allergic contact dermatitis and the epidemiological and clinical profile of children and adolescents with atopic dermatitis.

methodsCross-sectional, prospective study in patients between 4 and 18 years of age, with recalcitrant atopic dermatitis, treated at the Sanitary Dermatology Outpatient Clinic (RS). All patients underwent patch tests with a battery of pediatric allergens.

resultsThe prevalence of sensitization and allergic contact dermatitis in the evaluated patients was 37.07% (20/54) and 27.7% (15/54), respectively. The most frequent allergens were: nickel sulfate (16.7%), disperse blue (5.6%), and fragrance mix I (5.6%). Nickel was associated with the female sex (p = 0.019). STUDY LIMITATIONS: Sample size and selection, absence of a control group.

conclusionsA proportion of patients with recalcitrant atopic dermatitis may be sensitized to different allergens and may even have developed allergic contact dermatitis. Recognizing this context is important in the prevention strategy and management of the disease.

Indexed as

Dermatitis, Allergic ContactDermatitis, AtopicAdolescentAllergensChildCross-Sectional StudiesFemaleHumansPatch TestsProspective StudiesQuality of LifeAllergensAdolescentChildDermatitis, allergic contactDermatitis, atopicPatch tests

Identifiers

PMID35241316
PMCPMC9133262
OpenAlexW4214494126

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.