Evidence map›Paper›PMID 35241169›Full record

ArticleJournal of pharmaceutical policy and practice2022

Study on identification, assay and organoleptic quality of veterinary medicines in Ethiopia.

Belachew Tefera, Belachew Bacha, Sileshi Belew, Raffaella Ravinetto, Tenaw Andualem, Zerihun Abegaz, Ayalew Zelelew, Gudeta Uma, Tadese Setegn, Abdisa Hunduma and 3 more

Erratum issuedAbstract read
In one paragraph

Article in Journal of pharmaceutical policy and practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Belachew TeferaVeterinary Drug and Feed Administration and Control Authority (VDFACA), Animal Products, Veterinary Drug and Feed Quality Assessment Centre, P.O. Box 31303, Addis Ababa, Ethiopia. belachewteferazerihun@gmail.com.
Belachew BachaVeterinary Drug and Feed Administration and Control Authority (VDFACA), Animal Products, Veterinary Drug and Feed Quality Assessment Centre, P.O. Box 31303, Addis Ababa, Ethiopia.
Sileshi BelewJimma University Laboratory of Drug Quality (JuLaDQ) and School of Pharmacy, Jimma University, P.O. Box 378, Jimma, Ethiopia.
Raffaella RavinettoInstitute of Tropical Medicine, 2000, Antwerp, Belgium.
Tenaw AndualemFood and Agriculture Organization of the Untied Nation (FAO), P.O. Box 5536, Addis Ababa, Ethiopia.
Zerihun AbegazVeterinary Drug and Feed Administration and Control Authority (VDFACA), Animal Products, Veterinary Drug and Feed Quality Assessment Centre, P.O. Box 31303, Addis Ababa, Ethiopia.
Ayalew ZelelewVeterinary Drug and Feed Administration and Control Authority (VDFACA), Animal Products, Veterinary Drug and Feed Quality Assessment Centre, P.O. Box 31303, Addis Ababa, Ethiopia.
Gudeta UmaVeterinary Drug and Feed Administration and Control Authority (VDFACA), Animal Products, Veterinary Drug and Feed Quality Assessment Centre, P.O. Box 31303, Addis Ababa, Ethiopia.
Tadese SetegnVeterinary Drug and Feed Administration and Control Authority (VDFACA), Animal Products, Veterinary Drug and Feed Quality Assessment Centre, P.O. Box 31303, Addis Ababa, Ethiopia.
Abdisa HundumaVeterinary Drug and Feed Administration and Control Authority (VDFACA), Animal Products, Veterinary Drug and Feed Quality Assessment Centre, P.O. Box 31303, Addis Ababa, Ethiopia.
Dinsefa JemalVeterinary Drug and Feed Administration and Control Authority (VDFACA), Animal Products, Veterinary Drug and Feed Quality Assessment Centre, P.O. Box 31303, Addis Ababa, Ethiopia.
Diriba DabaVeterinary Drug and Feed Administration and Control Authority (VDFACA), Animal Products, Veterinary Drug and Feed Quality Assessment Centre, P.O. Box 31303, Addis Ababa, Ethiopia.
Bizuayehu BeleteVeterinary Drug and Feed Administration and Control Authority (VDFACA), Animal Products, Veterinary Drug and Feed Quality Assessment Centre, P.O. Box 31303, Addis Ababa, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMedicines of poor quality are currently prevailing problems undermining the quality of health care services in veterinary and human medicine. In this study, physico-chemical quality of veterinary medicines was evaluated.

methodsA total of 959 veterinary medicines samples were collected during routine regulatory activities, i.e. pre-registration, re-registration, consignment checking and post-marketing surveillance, in Ethiopia. The samples were transported to Animal Products, Veterinary Drug and Feed Quality Assessment Centre (APVD-FQAC), which is the quality control laboratory of the Veterinary Drug and Feed Administration and Control Authority (VDFACA) and stored until analysis. The samples were subjected to visual inspection and chemical analysis following the United States, European or British Pharmacopoeias, or manufacturer's methods.

resultsThe findings revealed that 12 (1.3%) of tested products showed defects in physical characteristics, packaging, or labelling information, while a total of 66 (6.9%) samples of the investigated products failed to comply with the Pharmacopoeias and supplier's specification limit set for assay. Of these, 60 samples did not comply with the minimum assay specification limit.

conclusionOverall, 8.2% of the investigated veterinary medicine samples did not comply with the specification set for the investigated quality attributes and thus were categorized as of poor quality. This indicates the need for continued strengthening of regulatory functions.

Indexed as

EthiopiaMedicinesQualityRegulatory authoritySurveillanceVeterinary

Identifiers

PMID35241169
PMCPMC8892721

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.