Evidence map›Paper›PMID 35241146›Full record

ReviewStem cell research & therapy2022

Combination of stem cell therapy and acupuncture to treat ischemic stroke: a prospective review.

Huidong Jia, Jia He, Lan Zhao, Chia-Chen Hsu, Xiaofeng Zhao, Yuzheng Du, Lin Han, Zhanfeng Cui, Xuemin Shi, Hua Ye

Open access · goldAbstract readReview
In one paragraph

Review in Stem cell research & therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 4 pooled it
6.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 4 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Huidong Jia *The Oxford Suzhou Centre for Advanced Research (OSCAR), Building A, 388 Ruo Shui Road, Suzhou Industrial Park, Jiangsu, People's Republic of China.
Jia He *First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, 88 Chang Ling Road, Xi Qing District, Tianjin, People's Republic of China.
Lan ZhaoFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine, 88 Chang Ling Road, Xi Qing District, Tianjin, People's Republic of China.
Chia-Chen HsuDepartment of Engineering Science, Institute of Biomedical Engineering, University of Oxford, Roosevelt Drive, Oxford, OX3 7DQ, UK.
Xiaofeng ZhaoFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine, 88 Chang Ling Road, Xi Qing District, Tianjin, People's Republic of China.
Yuzheng DuFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine, 88 Chang Ling Road, Xi Qing District, Tianjin, People's Republic of China.
Lin HanFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine, 88 Chang Ling Road, Xi Qing District, Tianjin, People's Republic of China.
Zhanfeng CuiThe Oxford Suzhou Centre for Advanced Research (OSCAR), Building A, 388 Ruo Shui Road, Suzhou Industrial Park, Jiangsu, People's Republic of China.
Xuemin Shi *First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, 88 Chang Ling Road, Xi Qing District, Tianjin, People's Republic of China.
Hua Ye *The Oxford Suzhou Centre for Advanced Research (OSCAR), Building A, 388 Ruo Shui Road, Suzhou Industrial Park, Jiangsu, People's Republic of China. hua.ye@eng.ox.ac.uk.ORCID 0000-0001-7613-6041
Tianjin University of Traditional Chinese Medicine · CNUniversity of Oxford · GB

Funding

Biotechnology and Biological Sciences Research Council BB/H008527/1
6 · The paper itself

Abstract

Stroke is the second leading cause globally that leads to severe disability and death. Stem cell therapy has been developed over the recent years to treat stroke and diminish the mortality and disability rate of brain injuries. Acupuncture, which can activate endogenous recovery via physical stimuli, has been applied to enhance the recovery and rehabilitation of stroke patients. Attempts have been made to combine stem cell therapy and acupuncture to treat stroke patients and have shown the promising results. This prospective review will look into the possible mechanisms of stem cell therapy and acupuncture and intend to undercover the potential benefit of the combined therapy. It intends to bridge the modern emerging stem cell therapy and traditional acupuncture at cellular and molecular levels and to demonstrate the potential benefit to improve clinical outcomes.

Indexed as

Acupuncture TherapyBrain IschemiaIschemic StrokeStrokeStroke RehabilitationHumansProspective StudiesStem Cell TransplantationTreatment OutcomeAcupunctureCombination therapyIschemic strokeStem cell therapy (cytotherapy)

Identifiers

PMID35241146
PMCPMC8896103
OpenAlexW4214874670

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.