ArticleCost effectiveness and resource allocation : C/E2022
Methodological challenges surrounding QALY estimation for paediatric economic evaluation.
Article in Cost effectiveness and resource allocation : C/E, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Methods of assessing value for money of UK-based early childhood public health interventions: a systematic literature review.British medical bulletin · 2023Pooled it
- Economic evaluations of interventions focusing on child abuse and neglect in high-income countries: a systematic review.Frontiers in psychiatry · 2023Pooled it
- A comparison of health-related quality of life between continuous ambulatory peritoneal dialysis and automated peritoneal dialysis in children with stage 5 chronic kidney disease in Thailand: a randomized controlled trial.Pediatric nephrology (Berlin, Germany) · 2025Trial
- Accounting for the Opportunity Cost of Children's Time in Economic Evaluation: Challenges and Frequently Asked Questions.Health economics · 2026Article
- Valuing health states for infants and toddlers: challenges and methodological considerations in EQ-TIPS preference elicitation.The European journal of health economics : HEPAC : health economics in prevention and care · 2026Article
- Article
- A scoping review of challenges in pediatric health technology assessments with a focus on pharmaceutical interventions.International journal of technology assessment in health care · 2025Article
- Comparing the Costs Associated with Anxiolytic Agents for Reducing Distress in Children Undergoing Laceration Repair in the Emergency Department.Journal of the American College of Emergency Physicians open · 2025Article
- Cost-effectiveness of a primary care-based Healthy Weight Clinic compared with usual care.Obesity (Silver Spring, Md.) · 2024Article
- Meeting the Challenges of Preference-Weighted Health-Related Quality-of-Life Measurement in Children.PharmacoEconomics · 2024Article
- Is well-becoming important for children and young people? Evidence from in-depth interviews with children and young people and their parents.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- A cost-effectiveness analysis of a universal, preventative-focused, parent and infant programme.BMC health services research · 2024Article
- Using Age-Specific Values for Pediatric HRQoL in Cost-Effectiveness Analysis: Is There a Problem to Be Solved? If So, How?PharmacoEconomics · 2023Article
- Review
- Is the cost-effectiveness of an early-childhood sleep intervention to prevent obesity affected by socioeconomic position?Obesity (Silver Spring, Md.) · 2023Article
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Abstract
Cost-utility analysis remains the preferred form of economic evaluation for health technology assessment, pricing and reimbursement authorities in several countries. The results of cost-utility analyses are commonly expressed in terms of incremental cost per quality-adjusted life year (QALY) gained where the QALY combines length of life and health-related quality of life in a single metric. This commentary provides an overview of key methodological challenges surrounding QALY estimation for paediatric economic evaluation. These challenges include issues surrounding the relevant attributes to incorporate into measurement instruments, appropriate respondents for the measurement and valuation tasks, perspectives adopted when completing valuation tasks, potential sources of bias in the description and valuation processes, and the paucity of psychometric evidence for existing measures. In addition, the commentary considers methodological challenges raised by research aimed at assessing whether a QALY gain by a child should be valued equally to a QALY gain by an adult.
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