Trial reportBMC oral health2022
Clinical application of concentrate growth factors combined with bone substitute in Alveolar ridge preservation of anterior teeth.
Trial report in BMC oral health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- Effect of Autologous Concentrated Growth Factor in Regenerative Dentistry: A Systematic Review and Meta-Analysis.JDR clinical and translational research · 2026Pooled it
- The histological and radiological evaluation of autologous peripheral venous blood concentrates in socket preservation: a systematic review and meta-analysis.Frontiers in dental medicine · 2025Pooled it
- Efficacy of concentrated growth factor (CGF) in the surgical treatment of oral diseases: a systematic review and meta-analysis.BMC oral health · 2023Pooled it
- Efficacy of different forms of concentrated growth factors combined with deproteinized bovine bone minerals in guided bone regeneration: a randomized clinical trial.BMC oral health · 2025Trial
- Application of sticky bone combined with concentrated growth factor (CGF) for horizontal alveolar ridge augmentation of anterior teeth: a randomized controlled clinical study.BMC oral health · 2024Trial
- Concentrated growth factor in oral bone regeneration: A narrative review.Regenerative therapy · 2026Review
- Soft Tissue Healing After Post-Extractive Alveolar Ridge Reconstruction Using a Magnesium Membrane-Based Regenerative Approach: A Preliminary Study.Journal of functional biomaterials · 2026Article
- Effects of Dual Wavelength Photobiomodulation on Osseointegration in Grafted Areas.Lasers in surgery and medicine · 2026Article
- Alveolar ridge preservation with lyophilized microspheres of human dental pulp stem cells following 3D dynamic osteogenic induction.Stem cells translational medicine · 2026Article
- Histologic evaluation of topical simvastatin effects on extraction sockets: A randomized controlled clinical trial.Journal of advanced periodontology & implant dentistry · 2025Article
- Self-assembling peptide nanofibers and nanoceramics in a model of alveolar bone repair: Insights from in vivo experiments and clinical trial.Regenerative therapy · 2025Article
- Article
- Healing of Extraction Sites after Alveolar Ridge Preservation Using Advanced Platelet-Rich Fibrin: A Retrospective Study.Bioengineering (Basel, Switzerland) · 2024Article
- Advancements in alveolar bone grafting and ridge preservation: a narrative review on materials, techniques, and clinical outcomes.Maxillofacial plastic and reconstructive surgery · 2024Review
- Guided Bone Regeneration: CGF and PRF Combined With Various Types of Scaffolds-A Systematic Review.International journal of dentistry · 2024Review
- Tomographic Evaluation of Alveolar Ridge Preservation Using Bone Substitutes and Collagen Membranes-A Retrospective Pilot Study.Dentistry journal · 2023Article
- Analysis of the effects of concentrated growth factor and low-level laser therapy on the bone healing.Heliyon · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the clinical effect of concentrated growth factors (CGF) combined with deproteinized bovine bone mineral (DBBM) on Alveolar ridge preservation during implantology.
methodsA total of 38 patients were selected and randomly divided into 2 groups, with 19 cases in each group. The extraction sockets were filled with DBBM with or without CGF. Visual analogue scale (VAS) pain score was recorded within1 week and Landry wound healing index (LWHI) was recorded at 1, 2 and 3 weeks after operation. CBCT was taken preoperatively and 3 and 6 months postoperatively to measure and compare the changes of vertical height, width and gray value of alveolar bone at extraction site. The changes of alveolar bone contour were observed clinically and compared between the two groups.
resultsThe VAS score of CGF group was lower than control group on the 1st and 3rd day after operation (P < 0.05). The LWHI of CGF group was higher than control group 1 week after operation (P < 0.05). The absorption of the labial and palatal plates height and the width in the CGF group was significantly less than the control group at 3 months (P < 0.05). The gray value of alveolar bone in CGF group was significantly higher than control group at 3 months (P < 0.05). There was no significant difference in new bone contour between the two groups (P > 0.05). 94.7% cases in CGF group did not undergo bone grafting, which was significantly higher than control group (78.9%).
conclusionsThe use of CGF combined with DBBM can help to reduce postoperative pain at the early stage of healing, form sufficient keratinized gingival tissue, effectively maintain the height and width of alveolar bone in the three-dimensional direction and provide good conditions for implant repair in the future.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.