Evidence map›Paper›PMID 35241020›Full record

ArticleBMC cancer2022

Primary central nervous system lymphoma high incidence and poor survival in Finnish population-based analysis.

Inka Puhakka, Hanne Kuitunen, Pekka Jäkälä, Eila Sonkajärvi, Taina Turpeenniemi-Hujanen, Aino Rönkä, Tuomas Selander, Miika Korhonen, Outi Kuittinen

Abstract read
In one paragraph

Article in BMC cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Primary central nervous system lymphoma.Nature reviews. Disease primers · 2023
    Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Inka PuhakkaDepartment of Neurology, Kuopio University Hospital, PL 100, 70029, Kuopio, KYS, Finland. inka.puhakka@kuh.fi.
Hanne KuitunenDepartment of Oncology, University of Oulu, Oulu University Hospital, Kajaanintie 50, 90220, Oulu, Finland.
Pekka JäkäläDepartment of Neurology, Kuopio University Hospital, PL 100, 70029, Kuopio, KYS, Finland.
Eila SonkajärviDepartment of Anesthesiology, University of Oulu, Oulu University Hospital, Kajaanintie 50, 90220, Oulu, Finland.
Taina Turpeenniemi-HujanenDepartment of Oncology, University of Oulu, Oulu University Hospital, Kajaanintie 50, 90220, Oulu, Finland.
Aino RönkäDepartment of Oncology, Kuopio University Hospital, PL 100, 70029, Kuopio, KYS, Finland.
Tuomas SelanderKuopio University Hospital, Science Service Center, PL 100, 70029, Kuopio, KYS, Finland.
Miika KorhonenDepartment of Neurology, Kuopio University Hospital, PL 100, 70029, Kuopio, KYS, Finland.
Outi KuittinenDepartment of Oncology, University of Oulu, Oulu University Hospital, Kajaanintie 50, 90220, Oulu, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe report here the first population-based incidence rates and prognosis of primary central nervous system lymphoma (PCNSL) in Finland.

methodsFinnish Cancer Registry data by histological diagnosis and tumor location (2007-2017) for cases with diffuse large B-cell lymphoma.

resultsDuring 2007-2017, 392 new cases of PCNSL were reported (195 males, 197 females). The average age-adjusted incidence was 0.68/100,000 person-years. Incidence for males was 0.74/100,000 and for females 0.63/100,000, respectively. The incidence was highest, 2.93/100,000, among people aged 75-79 years. Concerning all cases in 2007-2017 the 2-year age-adjusted relative survival rate was 33% and the corresponding 5-year survival rate was 26%. Among patients under the age of 70, the age-adjusted 5-year relative survival rate increased from 36% in 2007-2012 to 43% for 2013-2017. Among patients aged 70+ the corresponding survival rates were poor, 7 and 9%.

conclusionsPCNSL incidence in Finland is among the highest reported in the world. The annual increase in incidence was 2.4%. The prognosis is still dismal, especially in elderly patients.

Indexed as

AdultAgedAge DistributionCentral Nervous System NeoplasmsFemaleFinlandHumansIncidenceLymphomaMaleMiddle AgedPrognosisRegistriesSurvival RateCancer registryIncidencePcnslPrimary central nervous system lymphomaPrognosisSurvival

Identifiers

PMID35241020
PMCPMC8895860

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.