Evidence map›Paper›PMID 35240880›Full record

ArticlePsychology & health

Depressive symptoms and shorter survival in lung cancer: the role of leukocyte telomere length.

Chelsea J Siwik, Elizabeth Cash, Sandra E Sephton

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Psychology & health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Chelsea J SiwikOsher Center for Integrative Medicine, University of California, San Francisco, CA, USA.ORCID 0000-0003-1417-8582
Elizabeth CashDepartment of Otolaryngology-Head and Neck Surgery and Communicative Disorders, University of Louisville School of Medicine, Louisville, KY, USA.ORCID 0000-0003-4148-6927
Sandra E SephtonUofL Health - James Graham Brown Cancer Center, Louisville, KY, USA.ORCID 0000-0003-0585-0277
Brigham Young University · USUniversity of California, San Francisco · USUniversity of Louisville · US

Funding

Training Researchers in Clinical Integrative Medicine (TRIM) - NOSI supplementT32AT003997 · NCCIH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SHELLEY R ADLER, MARIA T CHAO · 2007 to 2026
$6.6M
NCCIH NIH HHS L30 AT011624NCCIH NIH HHS T32 AT003997
6 · The paper itself

Abstract

objectiveTo examine the association between depressive symptoms, leukocyte telomere length-a marker of cellular ageing, and survival amongst lung cancer patients.

designPatients with non-small cell lung cancer were recruited from a university-affiliated cancer center clinic. MAIN OUTCOME: Patients (

resultsAge at diagnosis and depressive symptoms, as measured by the CES-D, were associated with shorter leukocyte telomere length (

conclusionClinically meaningful levels of depressive symptoms are associated with shorter survival amongst lung cancer patients. These findings support the on-going efforts to screen all cancer patients for low mood and to investigate mechanisms linking depressive symptoms and shorter survival in cancer contexts.

Indexed as

depressionleukocyte telomere lengthLung cancersurvival

Identifiers

PMID35240880
PMCPMC9440155
OpenAlexW4214904080

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.