ArticlePLoS neglected tropical diseases2022
Sero-epidemiological survey of Coxiella burnetii in livestock and humans in Tana River and Garissa counties in Kenya.
Article in PLoS neglected tropical diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Prevalence and Risk Factors of Q Fever in Smallholder Dairy Farms in Kenya.Veterinary medicine and science · 2026Article
- Seroprevalence of Q fever among humans and animals in East Africa: a systematic review and meta-analysis.One health outlook · 2026Review
- Human and livestock exposure to Rift Valley fever virus and Coxiella burnetii in Eastern Ethiopia: a One Health cross-sectional study.Tropical medicine and health · 2026Article
- Molecular characterization ofFrontiers in veterinary science · 2026Article
- High prevalence of Q fever among patients clinically diagnosed with brucellosis in a Kenyan pastoralist community.Frontiers in epidemiology · 2026Article
- Molecular characterisation of tick-borne pathogens in cattle in kenya: insights from blood, ticks, and skin swab analyses.BMC veterinary research · 2025Article
- Sero-epidemiology of Coxiella burnetii in livestock and humans in Isiolo county Kenya.PLoS neglected tropical diseases · 2025Article
- Rift Valley fever virus and Coxiella burnetii infections among febrile patients, Eastern Ethiopia.PLoS neglected tropical diseases · 2025Article
- National serosurvey and risk mapping reveal widespread distribution of Coxiella burnetii in Kenya.Scientific reports · 2025Article
- Navigating Q fever: Current perspectives and challenges in outbreak preparedness.Open veterinary journal · 2024Review
- Agricultural extension service, technology adoption, and production risk nexus: Evidence from Bangladesh.Heliyon · 2024Article
- A sero-epidemiological analysis of Coxiella burnetii infection and its risk factors in livestock from Addis Ababa, Adama, and Modjo abattoirs and pastoral areas of Oromia, Ethiopia.PLoS neglected tropical diseases · 2024Article
- Comparison of test performance of a conventional PCR and two field-friendly tests to detectFrontiers in veterinary science · 2024Article
- Multiple pathogens co-exposure and associated risk factors among cattle reared in a wildlife-livestock interface area in Kenya.Frontiers in veterinary science · 2024Article
- Distribution and Prevalence ofInfectious disease reports · 2023Review
- A review of coxiellosis (Q fever) and brucellosis in goats and humans: Implications for disease control in smallholder farming systems in Southeast Asia.One health (Amsterdam, Netherlands) · 2023Review
- A scoping review of zoonotic parasites and pathogens associated with abattoirs in Eastern Africa and recommendations for abattoirs as disease surveillance sites.Frontiers in public health · 2023Article
- Screening forJournal of veterinary research · 2022Article
- Longitudinal Study of Selected Bacterial Zoonoses in Small Ruminants in Tana River County, Kenya.Microorganisms · 2022Article
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCoxiella burnetii is a widely distributed pathogen, but data on its epidemiology in livestock, and human populations remain scanty, especially in developing countries such as Kenya. We used the One Health approach to estimate the seroprevalance of C. burnetii in cattle, sheep, goats and human populations in Tana River county, and in humans in Garissa county, Kenya. We also identified potential determinants of exposure among these hosts.
methodsData were collected through a cross-sectional study. Serum samples were taken from 2,727 animals (466 cattle, 1,333 goats, and 928 sheep) and 974 humans and screened for Phase I/II IgG antibodies against C. burnetii using enzyme-linked immunosorbent assay (ELISA). Data on potential factors associated with animal and human exposure were collected using a structured questionnaire. Multivariable analyses were performed with households as a random effect to adjust for the within-household correlation of C. burnetii exposure among animals and humans, respectively.
resultsThe overall apparent seroprevalence estimates of C. burnetii in livestock and humans were 12.80% (95% confidence interval [CI]: 11.57-14.11) and 24.44% (95% CI: 21.77-27.26), respectively. In livestock, the seroprevalence differed significantly by species (p < 0.01). The highest seroprevalence estimates were observed in goats (15.22%, 95% CI: 13.34-17.27) and sheep (14.22%, 95% CI: 12.04-16.64) while cattle (3.00%, 95% CI: 1.65-4.99) had the lowest seroprevalence. Herd-level seropositivity of C. burnetii in livestock was not positively associated with human exposure. Multivariable results showed that female animals had higher odds of seropositivity for C. burnetii than males, while for animal age groups, adult animals had higher odds of seropositivity than calves, kids or lambs. For livestock species, both sheep and goats had significantly higher odds of seropositivity than cattle. In human populations, men had a significantly higher odds of testing positive for C. burnetii than women.
conclusionsThis study provides evidence of livestock and human exposure to C. burnetii which could have serious economic implications on livestock production and impact on human health. These results also highlight the need to establish active surveillance in the study area to reduce the disease burden associated with this pathogen.
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