Evidence map›Paper›PMID 35239442›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Developmentally distinct CD4

Joseph S Dolina, Joey Lee, Eugene L Moore, Jennifer L Hope, Donald T Gracias, Takaji Matsutani, Ashu Chawla, Jason A Greenbaum, Joel Linden, Stephen P Schoenberger

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Sympathetic regulation of the host immune response to bacterial sepsis.Clinical science (London, England : 1979) · 2025
    Review
  4. Recent Advances in Host Immune Mechanisms AgainstJournal of inflammation research · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Tregs tango with killer cells in acute infection.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Joseph S DolinaDivision of Developmental Immunology, La Jolla Institute for Immunology, La Jolla, CA 92037.ORCID 0000-0002-4602-8194
Joey LeeDivision of Developmental Immunology, La Jolla Institute for Immunology, La Jolla, CA 92037.
Eugene L MooreDivision of Vaccine Discovery, La Jolla Institute for Immunology, La Jolla, CA 92037.
Jennifer L HopeTumor Microenvironment and Cancer Immunology Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037.
Donald T GraciasDivision of Immune Regulation, La Jolla Institute for Immunology, La Jolla, CA 92037.
Takaji MatsutaniResearch and Development Department, Repertoire Genesis Incorporation, 567-0085 Ibaraki, Osaka, Japan.ORCID 0000-0002-4836-3375
Ashu ChawlaBioinformatics Core, La Jolla Institute for Immunology, La Jolla, CA 92037.
Jason A GreenbaumBioinformatics Core, La Jolla Institute for Immunology, La Jolla, CA 92037.ORCID 0000-0002-1381-0390
Joel LindenDivision of Developmental Immunology, La Jolla Institute for Immunology, La Jolla, CA 92037.ORCID 0000-0002-0689-1647
Stephen P SchoenbergerDivision of Developmental Immunology, La Jolla Institute for Immunology, La Jolla, CA 92037.
La Jolla Institute for Immunology · USSanford Burnham Prebys Medical Discovery Institute · US

Funding

Stimulating Neo-Antigen Specific T Cell Responses in Head and Neck CancersU01DE028227 · NIDCR · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI GUTKIND, JORGE SILVIO, RAO, ANJANA · 2018 to 2022
$4.6M
Cellular and Molecular Regulation of CD8+ T cell memoryR01AI107010 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI SCHOENBERGER, STEPHEN PHILIP · 2013 to 2017
$2.2M
Illumina HiSeq 2500 Sequencing SystemS10OD016262 · OD · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI RAO, ANJANA · 2013 to 2013
$600k
FACSAria II Cell SorterS10RR027366 · NCRR · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI CROFT, MICHAEL · 2011 to 2011
$514k
NCRR NIH HHS S10 RR027366NIAID NIH HHS R01 AI107010NIDCR NIH HHS U01 DE028227NIH HHS S10 OD016262
6 · The paper itself

Abstract

SignificanceThe CD4

Indexed as

5'-NucleotidaseAcute DiseaseAnimalsCD8-Positive T-LymphocytesListeria monocytogenesListeriosisMiceT-Lymphocytes, Regulatory5'-NucleotidaseCD73cyclic AMPFoxP3+ T regulatory cellgap junctionListeria monocytogenes

Identifiers

PMID35239442
PMCPMC8915796
OpenAlexW4214872454

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.