ArticleIntensive care medicine2022
Survival benefit of extracorporeal membrane oxygenation in severe COVID-19: a multi-centre-matched cohort study.
Article in Intensive care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- British societies guideline on the management of emergencies in patients on extracorporeal membrane oxygenation.Intensive care medicine · 2025Guideline
- Outcome of Emergency Pulmonary Lobectomy under ECMO Support in Patients with COVID-19.The Thoracic and cardiovascular surgeon · 2026Article
- Outcome of patients with COVID-19 supported by veno-venous extracorporeal membrane oxygenation with major bleeding: a single centre experience.BMC anesthesiology · 2025Article
- Extracorporeal life support for adult patients with ARDS.Intensive care medicine · 2025Review
- Characteristics of the top 100 cited original studies on extracorporeal membrane oxygenation: a bibliometric analysis.Journal of thoracic disease · 2024Article
- Commentary: Who and when to leave behind: Difficult decisions around extracorporeal membrane oxygenation selection in coronavirus disease 2019.The Journal of thoracic and cardiovascular surgery · 2024Article
- Survival and Long-Term Functional Status of COVID-19 Patients Requiring Prolonged Extracorporeal Membrane Oxygenation Support.Annals of the American Thoracic Society · 2024Observational
- Mapping a Decade (2014-2024) of Research on Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome: A Visual Analysis with CiteSpace and VOSviewer.Journal of multidisciplinary healthcare · 2024Article
- ESICM guidelines on acute respiratory distress syndrome: definition, phenotyping and respiratory support strategies.Intensive care medicine · 2023Article
- Prone Positioning in Mechanically Ventilated COVID-19 Patients: Timing of Initiation and Outcomes.Journal of clinical medicine · 2023Article
- The Use of Extracorporeal Membrane Oxygenation for COVID-19: Lessons Learned.Clinics in chest medicine · 2023Review
- Extracorporeal membrane oxygenation in COVID-19: Results of the Croatian Extracorporeal Membrane Oxygenation Referral Center.The International journal of artificial organs · 2023Article
- Multi-horizon predictive models for guiding extracorporeal resource allocation in critically ill COVID-19 patients.Journal of the American Medical Informatics Association : JAMIA · 2023Article
- Mechanical power of ventilation and driving pressure: two undervalued parameters for pre extracorporeal membrane oxygenation ventilation and during daily management?Critical care (London, England) · 2023Review
- Extracorporeal Membrane Oxygenation for COVID-19: Comparison of Outcomes to Non-COVID-19-Related Viral Acute Respiratory Distress Syndrome From the Extracorporeal Life Support Organization Registry.Critical care explorations · 2023Article
- Extracorporeal membrane oxygenation in COVID-19 associated acute respiratory distress syndrome: A narrative review.Journal of intensive medicine · 2023Review
- Massive Airway Hemorrhage in Severe COVID-19 and the Role of Endotracheal Tube Clamping.Infection and drug resistance · 2023Article
- New and personalized ventilatory strategies in patients with COVID-19.Frontiers in medicine · 2023Review
- Extracorporeal Membrane Oxygenation to Support COVID-19 Patients: A Propensity-Matched Cohort Study.Critical care research and practice · 2023Article
- Outcomes of Extracorporeal Membrane Oxygenation in COVID-19-Induced Acute Respiratory Distress Syndrome: An Inverse Probability Weighted Analysis.Critical care explorations · 2022Article
Corrections and comments
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- Erratum issued
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeExtracorporeal membrane oxygenation (ECMO) has become an established therapy for severe respiratory failure in coronavirus disease 2019 (COVID-19). The added benefit of receiving ECMO in COVID-19 remains uncertain. The aim of this study is to analyse the impact of receiving ECMO at specialist centres on hospital mortality.
methodsA multi-centre retrospective study was conducted in COVID-19 patients from 111 hospitals, referred to two specialist ECMO centres in the United Kingdom (UK) (March 2020 to February 2021). Detailed covariate data were contemporaneously curated from electronic referral systems. We analysed added benefit of ECMO treatment in specialist centres using propensity score matching techniques.
results1363 patients, 243 receiving ECMO, were analysed. The best matching technique generated 209 matches, with a marginal odds ratio (OR) for mortality of 0.44 (95% CI 0.29-0.68, p < 0.001) and absolute mortality reduction of 18.2% (44% vs 25.8%, p < 0.001) for treatment with ECMO in a specialist centre.
conclusionWe found ECMO provided at specialist centres conferred significant survival benefit. Where resources and specialism allow, ECMO should be widely offered.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.