Evidence map›Paper›PMID 35238662›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Purging of deleterious burden in the endangered Iberian lynx.

Daniel Kleinman-Ruiz, Maria Lucena-Perez, Beatriz Villanueva, Jesús Fernández, Alexander P Saveljev, Mirosław Ratkiewicz, Krzysztof Schmidt, Nicolas Galtier, Aurora García-Dorado, José A Godoy

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
17.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 98 citations in OpenAlex.

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  20. Whole-genome duplication increases genetic diversity and load in outcrossingProceedings of the National Academy of Sciences of the United States of America · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 5 countries.

Daniel Kleinman-RuizDepartment of Integrative Ecology, Estación Biológica de Doñana, Consejo Superior de Investigaciones Cientificas, 41092 Seville, Spain.ORCID 0000-0003-2438-7329
Maria Lucena-PerezDepartment of Integrative Ecology, Estación Biológica de Doñana, Consejo Superior de Investigaciones Cientificas, 41092 Seville, Spain.
Beatriz VillanuevaDepartamento de Mejora Genética Animal, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria, 28040 Madrid, Spain.
Jesús FernándezDepartamento de Mejora Genética Animal, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria, 28040 Madrid, Spain.ORCID 0000-0001-8269-1893
Alexander P SaveljevDepartment of Animal Ecology, Russian Research Institute of Game Management and Fur Farming, 610000 Kirov, Russia.ORCID 0000-0002-8103-5787
Mirosław RatkiewiczFaculty of Biology, University of Białystok, 15-245 Białystok, Poland.ORCID 0000-0003-2929-3612
Krzysztof SchmidtMammal Research Institute, Polish Academy of Sciences, 17-230 Białowieża, Poland.ORCID 0000-0002-9043-291X
Nicolas GaltierInstitut des Sciences de l'Evolution, Université Montpellier, CNRS, Institut de Recherche pour le Développement, 34090 Montpellier, France.
Aurora García-DoradoDepartamento de Genética, Fisiología y Microbiología, Facultad de Biología, Universidad Complutense, 28040 Madrid, Spain.
José A GodoyDepartment of Integrative Ecology, Estación Biológica de Doñana, Consejo Superior de Investigaciones Cientificas, 41092 Seville, Spain.ORCID 0000-0001-7502-9471
Consejo Superior de Investigaciones Científicas · ESInstituto Nacional de Investigación y Tecnología Agraria y Alimentaria · ESUniversidad Complutense de Madrid · ESCentre National de la Recherche Scientifique · FRForestry and Game Management Research Institute · CZMammal Research Institute · PLUniversity of Białystok · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SignificanceThe dynamics of deleterious variation under contrasting demographic scenarios remain poorly understood in spite of their relevance in evolutionary and conservation terms. Here we apply a genomic approach to study differences in the burden of deleterious alleles between the endangered Iberian lynx (

Indexed as

Endangered SpeciesAnimalsBiological EvolutionGenetics, PopulationGenetic VariationInbreedingLynxMutationPolymorphism, Single Nucleotideconservationgenetic loadpopulation genomicspurgingsmall populations

Identifiers

PMID35238662
PMCPMC8931242
OpenAlexW4214892203

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.