Evidence map›Paper›PMID 35238623›Full record

ArticleNucleic acid therapeutics2022

2'-

Dmytro Honcharenko, Cristina S J Rocha, Karin E Lundin, Jyotirmoy Maity, Stefan Milton, Ulf Tedebark, Merita Murtola, Malgorzata Honcharenko, Andis Slaitas, C I Edvard Smith and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Nucleic acid therapeutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. A Study on Synthesis and Upscaling of 2'-Molecules (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Dmytro HoncharenkoDepartment of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden.
Cristina S J RochaDepartment of Laboratory Medicine, Clinical Research Center, Karolinska Institutet, Karolinska University Hospital, Huddinge, Sweden.ORCID 0000-0002-6008-9532
Karin E LundinDepartment of Laboratory Medicine, Clinical Research Center, Karolinska Institutet, Karolinska University Hospital, Huddinge, Sweden.
Jyotirmoy MaityDepartment of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden.
Stefan MiltonDepartment of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden.
Ulf TedebarkDepartment of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden.
Merita MurtolaDepartment of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden.
Malgorzata HoncharenkoDepartment of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden.
Andis SlaitasSyntagon Baltic, Babites novads, Latvia.
C I Edvard SmithDepartment of Laboratory Medicine, Clinical Research Center, Karolinska Institutet, Karolinska University Hospital, Huddinge, Sweden.
Rula ZainDepartment of Laboratory Medicine, Clinical Research Center, Karolinska Institutet, Karolinska University Hospital, Huddinge, Sweden.
Roger StrömbergDepartment of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden.ORCID 0000-0002-7902-2688
Karolinska Institutet · SEKarolinska University Hospital · SEBaltic Studies Centre · LV

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

2'-

Indexed as

Oligonucleotides, AntisensePhosphorothioate OligonucleotidesCell LineOligonucleotides, AntisensePhosphorothioate Oligonucleotides2′-O-(N-(aminoethyl)carbamoyl)methyl modificationcell-penetrating ONscellular uptakeoligonucleotide–peptide conjugatephosphorothioate linkagesplice-switching oligonucleotides

Identifiers

PMID35238623
PMCPMC9221157
OpenAlexW4214951644

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.