Evidence map›Paper›PMID 35238340›Full record

ArticleCerebral cortex (New York, N.Y. : 1991)2022

Examining the neural correlates of error awareness in a large fMRI study.

Gezelle Dali, Méadhbh Brosnan, Jeggan Tiego, Beth P Johnson, Alex Fornito, Mark A Bellgrove, Robert Hester

Abstract read
In one paragraph

Article in Cerebral cortex (New York, N.Y. : 1991), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  10. Edge-Based General Linear Models Capture Moment-to-Moment Fluctuations in Attention.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gezelle DaliMelbourne School of Psychological Sciences, The University of Melbourne, Parkville, VIC 3010, Australia.ORCID 0000-0003-1613-2596
Méadhbh BrosnanDepartment of Experimental Psychology, University of Oxford, Oxford, OX2 6GG, UK.
Jeggan TiegoThe Turner Institute for Brain and Mental Health, School of Psychological Sciences, and Monash Biomedical Imaging, Monash University, Melbourne, VIC, 3800, Australia.
Beth P JohnsonThe Turner Institute for Brain and Mental Health, School of Psychological Sciences, and Monash Biomedical Imaging, Monash University, Melbourne, VIC, 3800, Australia.
Alex FornitoThe Turner Institute for Brain and Mental Health, School of Psychological Sciences, and Monash Biomedical Imaging, Monash University, Melbourne, VIC, 3800, Australia.
Mark A BellgroveThe Turner Institute for Brain and Mental Health, School of Psychological Sciences, and Monash Biomedical Imaging, Monash University, Melbourne, VIC, 3800, Australia.
Robert HesterMelbourne School of Psychological Sciences, The University of Melbourne, Parkville, VIC 3010, Australia.

Funding

Wellcome Trust 203139/Z/16/Z
6 · The paper itself

Abstract

Goal-directed behavior is dependent upon the ability to detect errors and implement appropriate posterror adjustments. Accordingly, several studies have explored the neural activity underlying error-monitoring processes, identifying the insula cortex as crucial for error awareness and reporting mixed findings with respect to the anterior cingulate cortex (ACC). Variable patterns of activation have previously been attributed to insufficient statistical power. We therefore sought to clarify the neural correlates of error awareness in a large event-related functional magnetic resonance imaging (fMRI) study. Four hundred and two healthy participants undertook the error awareness task, a motor Go/No-Go response inhibition paradigm in which participants were required to indicate their awareness of commission errors. Compared to unaware errors, aware errors were accompanied by significantly greater activity in a network of regions, including the insula cortex, supramarginal gyrus (SMG), and midline structures, such as the ACC and supplementary motor area (SMA). Error awareness activity was related to indices of task performance and dimensional measures of psychopathology in selected regions, including the insula, SMG, and SMA. Taken together, we identified a robust and reliable neural network associated with error awareness.

Indexed as

Gyrus CinguliMagnetic Resonance ImagingAwarenessHumansInhibition, PsychologicalParietal LobeTask Performance and Analysisanterior cingulate cortexerror awarenesserror-monitoring processesfunctional magnetic resonance imaginginsula

Identifiers

PMID35238340
PMCPMC9837605

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.