Evidence map›Paper›PMID 35237950›Full record

ArticleInfection2022

Positive peritoneal swab in SARS-CoV-2 patients undergoing abdominal emergency surgery: effect or cause?

Dario Tartaglia, Andrea Barberis, Federico Coccolini, Mauro Pistello, Mariangela Rutigliani, Massimo Chiarugi

Open access · hybridAbstract read
In one paragraph

Article in Infection, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Dario TartagliaGeneral, Emergency and Trauma Surgery Department, Pisa University Hospital, Pisa, Italy. dario.tartaglia@unipi.it.ORCID http://orcid.org/0000-0003-1615-3370
Andrea BarberisDepartment of Abdominal Surgery, General and Hepatopancreatobiliary Surgery Unit, Galliera Hospital, Genoa, Italy.
Federico CoccoliniGeneral, Emergency and Trauma Surgery Department, Pisa University Hospital, Pisa, Italy.
Mauro PistelloVirology Unit, Pisa University Hospital, Pisa, Italy.
Mariangela RutiglianiDepartment of Laboratory and Service, Histological and Anatomical Pathology, E.O. Galliera Hospital, Genoa, Italy.
Massimo ChiarugiGeneral, Emergency and Trauma Surgery Department, Pisa University Hospital, Pisa, Italy.
Azienda Ospedaliera Universitaria Pisana · ITEnte Ospedaliero Ospedali Galliera · ITUniversity of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe presence of the SARS-CoV-2 in the peritoneal fluid is a matter of debate in the COVID-19 literature. The study aimed to report the prevalence of SARS-CoV-2 in the peritoneal fluid of patients with nasopharyngeal swab tested positive for SARS-CoV-2 undergoing emergency surgery and review the literature.

methodsThe present study was conducted between March 2020 and June 2021. Diagnosis of SARS-CoV-2 positivity was confirmed by preoperative real-time reverse transcriptase-polymerase chain reaction (RT-PCR).

resultsEighteen patients with positive nasopharyngeal swabs were operated in emergency in two third-level Italian hospitals. In 13 of these patients (72%), a peritoneal swab was analyzed: SARS-CoV-2 RNA was found in the abdominal fluid of two patients (15%). Neither of them had visceral perforation and one patient died. In ten patients with negative peritoneal swabs, visceral perforation and mortality rates were 30% and 20%, respectively.

conclusionSARS-CoV-2 peritoneal positivity is rare. Abdominal surgery can, therefore, be safely performed in patients with COVID-19 using standard precautions. The correlation with a visceral perforation is not evaluable. The clinical outcomes seem uninfluenced by the viral colonization of the peritoneum. Assessment in large series to provide definitive answers about the involvement of the SARS-CoV-2 in the peritoneum will be challenging to coordinate.

Indexed as

COVID-19SARS-CoV-2COVID-19 TestingHumansReal-Time Polymerase Chain ReactionRNA, ViralRNA, ViralCoronavirusCOVID-19LaparoscopyLaparotomyPeritoneal fluidSARS-CoV-2

Identifiers

PMID35237950
PMCPMC8890010
OpenAlexW4214940247

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.