Evidence map›Paper›PMID 35237865›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2022

Association of spinal anomalies with spondylolysis and spina bifida occulta.

Masatoshi Morimoto, Kosuke Sugiura, Kosaku Higashino, Hiroaki Manabe, Fumitake Tezuka, Keizo Wada, Kazuta Yamashita, Shoichiro Takao, Koichi Sairyo

Abstract read
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In one paragraph

Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Radiological Insights Into Spina Bifida Occulta in Adults:Sultan Qaboos University medical journal · 2025
    Article
  4. Article
  5. Article
  6. Magnetic resonance imaging (MRI)Quantitative imaging in medicine and surgery · 2024
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Masatoshi MorimotoDepartment of Diagnostic Orthopedics, Tokushima University Graduate School, Institute of Health Sciences, 3-18-15 Kuramoto, Tokushima, 770-8501, Japan. masa_m_089034@yahoo.co.jp.
Kosuke SugiuraDepartment of Diagnostic Orthopedics, Tokushima University Graduate School, Institute of Health Sciences, 3-18-15 Kuramoto, Tokushima, 770-8501, Japan.
Kosaku HigashinoDepartment of Orthopedics, Shikoku Medical Center for Children and Adults, 2-1-1 Senyu-cho, Zentsuji-shi, Kagawa, 765-8507, Japan.
Hiroaki ManabeDepartment of Diagnostic Orthopedics, Tokushima University Graduate School, Institute of Health Sciences, 3-18-15 Kuramoto, Tokushima, 770-8501, Japan.
Fumitake TezukaDepartment of Diagnostic Orthopedics, Tokushima University Graduate School, Institute of Health Sciences, 3-18-15 Kuramoto, Tokushima, 770-8501, Japan.
Keizo WadaDepartment of Diagnostic Orthopedics, Tokushima University Graduate School, Institute of Health Sciences, 3-18-15 Kuramoto, Tokushima, 770-8501, Japan.
Kazuta YamashitaDepartment of Diagnostic Orthopedics, Tokushima University Graduate School, Institute of Health Sciences, 3-18-15 Kuramoto, Tokushima, 770-8501, Japan.
Shoichiro TakaoDepartment of Diagnostic Radiology, Tokushima University Graduate School, Institute of Health Sciences, 3-18-15 Kuramoto, Tokushima, 770-8501, Japan.
Koichi SairyoDepartment of Diagnostic Orthopedics, Tokushima University Graduate School, Institute of Health Sciences, 3-18-15 Kuramoto, Tokushima, 770-8501, Japan.
Tokushima University · JPShikoku Medical Center for Children and Adults · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the association of spinal anomalies with lumbar spondylolysis and spina bifida occulta (SBO).

methodsA total of 1190 patients with thoracic, abdominal, and pelvic computed tomography scans available were categorized according to the number of presacral (thoracic and lumbar) mobile vertebrae and the presence or absence of lumbosacral transitional vertebrae (LSTV). The prevalence of spondylolysis and SBO and the association of spinal anomalies with these disorders were evaluated.

resultsNormal morphology (17 mobile vertebra with no LSTV) was found in 607 men (86.5%) and 419 women (85.9%) and about 14% of patients had anomalies. Spondylolysis was found in 74 patients (6.2%), comprising 54 men (7.7%) and 20 women (4.1%). SBO involving the lumbar spine was found in 9 men (1.3%) and 2 women (0.4%). Spondylolysis was significantly more common in men with 18 vertebrae without LSTV (21.1%) than in those with 17 vertebrae without LSTV (7.2%) (p = 0.002). The prevalence of spinal anomalies was 55.6% in men and 50.0% in women with SBO that included a lumbar level was significantly higher than in both men (13.5%, p < 0.001) and women (4.8%, p = 0.003) without SBO.

conclusionThese findings indicate that there is a relationship between spinal anomalies and both spondylolysis and SBO, which may lead to elucidation of the mechanism of onset of spondylolysis and improve its treatment and prognosis. Awareness that patients with SBO involving the lumbar spine have an increased likelihood of a spinal anomaly may help to prevent level errors during spinal surgery.

Indexed as

Spina Bifida OccultaSpondylolysisFemaleHumansLumbar VertebraeLumbosacral RegionMaleTomography, X-Ray ComputedSpina bifida occultaSpinal anomalySpondylolysisTransitional vertebra

Identifiers

PMID35237865
OpenAlexW4214835138

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.