ArticleFoot & ankle orthopaedics2022
Ankle Fracture and Length of Stay in US Adult Population Using Data From the National COVID Cohort Collaborative.
Article in Foot & ankle orthopaedics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 6 citations in OpenAlex.
- Navigating Ankle Fracture Surgery in the Shadow of COVID-19.Foot & ankle specialist · 2026Article
- A temporal analysis of perioperative complications following COVID-19 infection in patients undergoing lumbar spinal fusion: When is it safe to proceed?North American Spine Society journal · 2023Article
- Time-to-Surgery and Short-Term Outcomes of Trimalleolar Ankle Fracture During the COVID-19 Pandemic.Cureus · 2023Article
- MedML: Fusing medical knowledge and machine learning models for early pediatric COVID-19 hospitalization and severity prediction.iScience · 2022Article
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Authors and funding
11 authors at 6 institutions in 1 country.
Funding
Abstract
backgroundThe National COVID Cohort Collaborative (N3C) is an innovative approach to integrate real-world clinical observations into a harmonized database during the time of the COVID-19 pandemic when clinical research on ankle fracture surgery is otherwise mostly limited to expert opinion and research letters. The purpose of this manuscript is to introduce the largest cohort of US ankle fracture surgery patients to date with a comparison between lab-confirmed COVID-19-positive and COVID-19-negative.
methodsA retrospective cohort of adults with ankle fracture surgery using data from the N3C database with patients undergoing surgery between March 2020 and June 2021. The database is an NIH-funded platform through which the harmonized clinical data from 46 sites is stored. Patient characteristics included body mass index, Charlson Comorbidity Index, and smoking status. Outcomes included 30-day mortality, overall mortality, surgical site infection (SSI), deep SSI, acute kidney injury, pulmonary embolism, deep vein thrombosis, sepsis, time to surgery, and length of stay. COVID-19-positive patients were compared to COVID-19-negative controls to investigate perioperative outcomes during the pandemic.
resultsA total population of 8.4 million patient records was queried, identifying 4735 adults with ankle fracture surgery. The COVID-19-positive group (n=158, 3.3%) had significantly longer times to surgery (6.5 ± 6.6 vs 5.1 ± 5.5 days,
conclusionPatients with ankle fracture surgery had longer time to surgery and prolonged hospitalizations in COVID-19-positive patients compared to those who tested negative (average delay was about 1 day and increased length of hospitalization was about 4 days). Few perioperative events were observed in either group. Overall, the risks associated with COVID-19 were measurable but not substantial.
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