Evidence map›Paper›PMID 35237634›Full record

ArticleFrontiers in medicine2022

Case Report: Myocarditis After COVID-19 Vaccination - Case Series and Literature Review.

Samuel Nunn, Johannes Kersten, Marijana Tadic, Alexander Wolf, Birgid Gonska, Elina Hüll, Hanna Dietenberger, Wolfgang Rottbauer, Dominik Buckert

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 4 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 4 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
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  5. "Bridging the clinical, molecular and genetic perspectives on myocarditis in post-COVID-19 era".International journal of cardiology. Cardiovascular risk and prevention · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Samuel NunnDepartment for Internal Medicine II, University of Ulm, Ulm, Germany.
Johannes KerstenDepartment for Internal Medicine II, University of Ulm, Ulm, Germany.
Marijana TadicDepartment for Internal Medicine II, University of Ulm, Ulm, Germany.
Alexander WolfDepartment for Internal Medicine II, University of Ulm, Ulm, Germany.
Birgid GonskaDepartment for Internal Medicine II, University of Ulm, Ulm, Germany.
Elina HüllDepartment for Internal Medicine II, University of Ulm, Ulm, Germany.
Hanna DietenbergerDepartment of Pathology, University of Ulm, Ulm, Germany.
Wolfgang RottbauerDepartment for Internal Medicine II, University of Ulm, Ulm, Germany.
Dominik BuckertDepartment for Internal Medicine II, University of Ulm, Ulm, Germany.
Universität Ulm · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe ongoing COVID-19 pandemic demands a series of measures and, above all, the vaccination of a substantial proportion of the population. Acute myocarditis is a rare complication of the widely used mRNA-based vaccines. CASE PRESENTATION: We present a case series of four patients (three men and one woman, 16 to 47 years old) with acute pericarditis/myocarditis 3 to 17 days after mRNA vaccination. They presented with chest pain, fever, and flu-like symptoms. Diagnosis was made based on the synopsis of clinical presentation, elevated levels of troponin T and NT-proBNP, impaired systolic function on echocardiography, and findings in non-invasive tissue characterization by cardiovascular magnetic resonance imaging. Two patients also underwent endomyocardial biopsies. As none of the patients showed signs of cardiogenic shock, they were discharged from ward care only a few days after their initial presentations.

conclusionsOur data are consistent with other case reports of myocarditis early after mRNA vaccination and demonstrate the need for multimodal diagnostics. In view of its rarity and mild course, the risk-benefit ratio of vaccination remains positive compared to potential SARS-CoV-2 infection.

Indexed as

cardiovascular magnetic resonance (CMR)echocardiographyendomyocardial biopsy (EMB)mRNA vaccinesmyocarditisSARS-CoV-2speckle tracking

Identifiers

PMID35237634
PMCPMC8882906
OpenAlexW4212937452

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.