Evidence map›Paper›PMID 35237588›Full record

ArticleFrontiers in bioengineering and biotechnology2021

Application of Tilapia Skin Acellular Dermal Matrix to Induce Acute Skin Wound Repair in Rats.

Kangning Lv, Lei Wang, Xiaoli He, Wenjun Li, Lei Han, Song Qin

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
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  6. International journal of molecular sciences · 2025
    Article
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  8. Review
  9. Article
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  11. Article
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  14. Review
  15. Review
  16. Acellular fish skin for wound healing.International wound journal · 2023
    Review
  17. Article
  18. Preparation of fish decalcified bone matrix and its bone repair effect in rats.Frontiers in bioengineering and biotechnology · 2023
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Kangning LvSchool of Ocean, Yantai University, Yantai, China.
Lei WangYantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai, China.
Xiaoli HeYantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai, China.
Wenjun LiYantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai, China.
Lei HanSchool of Life Science, Yantai University, Yantai, China.
Song QinYantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai, China.
Chinese Academy of Sciences · CNYantai Institute of Coastal Zone Research · CNYantai University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracellular matrix (ECM) material with good biological activity is essential to simulate cell growth microenvironment, induce cell infiltration and angiogenesis, and promote the repair of large area acute skin wound. In this study, tilapia skin acellular dermal matrix (TADM) was prepared to simulate ECM microenvironment, which can promote substantial area acute wound healing in rats. The main component of TADM is type I collagen, which has good physical and chemical properties, biological activity and cell adhesion. TADM is a form of biomaterial with low immunogenicity, low risk of prion infection and lower economic cost than other related materials such as mammalian collagen biomaterials. Our results show that TADM can guide cell infiltration, angiogenesis, regulate the expression and secretion of inflammatory and skin repair correlated factors to promote tissue healing.

Indexed as

acellular dermal matrixcollagenrepairtilapia skinwound

Identifiers

PMID35237588
PMCPMC8882825
OpenAlexW4213124915

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.