Evidence map›Paper›PMID 35237574›Full record

ArticleFrontiers in bioengineering and biotechnology2022

Removal of Environmental Nanoparticles Increases Protein Synthesis and Energy Production in Healthy Humans.

Eduardo Antuña, Juan Carlos Bermejo-Millo, Enrique Caso-Onzain, Enrique Caso-Peláez, Yaiza Potes, Ana Coto-Montes

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06968000 (Pilot, Controlled, Double-blind Study to Evaluate the Effect of the Exposome Anionic Enrichment System), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06968000 phase1 / phase2recruitingnot on this mapstarted 2025, after this paper: background citation

Pilot, Controlled, Double-blind Study to Evaluate the Effect of the Exposome Anionic Enrichment System (Biow) on Hospital Recovery Quality, Clinical Response, and Sleep Quality in Postoperative Patients

TypeinterventionalSponsorInstituto de Investigación Sanitaria de la Fundación Jiménez DíazRan2025 to 2027Enrolled150ConditionsInflammatory Response After Surgery, Postoperative RecoveryArmsEOX Anion-Enriched Hospital Room
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Eduardo AntuñaDepartment of Morphology and Cell Biology, Faculty of Medicine, University of Oviedo, Oviedo, Spain.
Juan Carlos Bermejo-MilloDepartment of Morphology and Cell Biology, Faculty of Medicine, University of Oviedo, Oviedo, Spain.
Enrique Caso-OnzainInnovación Unit, BiowAir Total Systems SL, C/Michel Faraday, Gijón, Spain.
Enrique Caso-PeláezScientific CEO MyOmics SL, Gijón, Spain.
Yaiza PotesDepartment of Morphology and Cell Biology, Faculty of Medicine, University of Oviedo, Oviedo, Spain.
Ana Coto-MontesDepartment of Morphology and Cell Biology, Faculty of Medicine, University of Oviedo, Oviedo, Spain.
Universidad de Oviedo · ESInstituto de Investigación Sanitaria del Principado de Asturias · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Currently, industrial activity causes the environmental release of nanoparticles that have multiple adverse effects on population health. There is a clear correlation between the increase in particulate air pollution and the increases in mortality and morbidity rates in both adults and children, which demonstrates the toxic effects of these particles. However, the effect of particle removal on healthy individuals is unknown. Thus, in this preliminary study, we showed, for the first time, how the filtering equipment that we used significantly reduced a large amount of nanoparticles in a minimum time and induced a reduction of oxidative damage in healthy individuals of both sexes after 25, 50 and 100 days of exposure. These effects led to increased protein synthesis and enhanced mitochondrial efficiency, thus resulting in a highly significant triggering of ATP synthesis. These results not only provide insight into the chronic effects that environmental nanoparticles have on individuals prior to the development of pathologies but also demonstrate a system capable of reversing nanoparticle toxicity and allowing cellular energy recovery.

Indexed as

air pollutionATPfiltrationmitochondriananoparticlesprotein synthesis p70S6Ktotal antioxidant activity

Identifiers

PMID35237574
PMCPMC8883322
OpenAlexW4212829471

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.