Evidence map›Paper›PMID 35237506›Full record

ArticleFrontiers in oncology2022

Durable Clinical Response to ALK Tyrosine Kinase Inhibitors in Epithelioid Inflammatory Myofibroblastic Sarcoma Harboring

Zhan Wang, Yan Geng, Ling-Yan Yuan, Miao-Miao Wang, Chen-Yang Ye, Li Sun, Wei-Ping Dai, Yuan-Sheng Zang

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 28 citations in OpenAlex.

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  13. Update of Diagnosis and Targeted Therapy for ALKCurrent treatment options in oncology · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Zhan WangDepartment of Medical Oncology, Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Yan GengDepartment of Nursing, Shanghai Jing'an District Zhabei Central Hospital, Shanghai, China.
Ling-Yan YuanDepartment of Medical Oncology, Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Miao-Miao WangDepartment of Medical Oncology, Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Chen-Yang YeDepartment of Medical Oncology, Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Li SunDepartment of Medical Oncology, Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Wei-Ping DaiDepartment of Medical Oncology, Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Yuan-Sheng ZangDepartment of Medical Oncology, Second Affiliated Hospital of Naval Medical University, Shanghai, China.
Shanghai Changzheng Hospital · CNShanghai Zhabei District Shibei Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory myofibroblastic tumor (IMT) is a rare mesenchymal neoplasm and patients with IMT tend to have a favorable outcome after complete surgical resection. However, some tumors of IMT cases have recurred and grown rapidly after successful surgery. Epithelioid inflammatory myofibroblastic sarcoma (EIMS) is a highly aggressive intra-abdominal IMT variant with epithelioid-to-round cell morphology. Currently, no standard therapy exists for recurrent or invasive IMTs and EIMS, but anaplastic lymphoma kinase (ALK) tyrosine kinase inhibitors (TKIs) are recommended for those harboring

Indexed as

alectinibALK L1196MALK R1192Pceritinibcrizotinib resistanceepithelioid inflammatory myofibroblastic sarcomaIMTPRRC2B-ALK

Identifiers

PMID35237506
PMCPMC8882834
OpenAlexW4212878940

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.