Evidence map›Paper›PMID 35237497›Full record

ArticleCureus2022

Treatment of Central Vertigo With Low Dose Olanzapine: Report of Two Cases.

Connie Jiang, Anusha Lekshminarayanan, Ihsan Balkaya, Alal Uddin, Sheital Bavishi, Eric Altschuler

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Connie JiangPhysical Medicine and Rehabilitation, Private Practice, Fairfax, USA.
Anusha LekshminarayananPhysical Medicine and Rehabilitation, Metropolitan Hospital Center, New York, USA.
Ihsan BalkayaPhysical Medicine and Rehabilitation, Metropolitan Hospital Center, New York, USA.
Alal UddinPhysical Medicine and Rehabilitation, Metropolitan Hospital Center, New York, USA.
Sheital BavishiPhysical Medicine and Rehabilitation, The Ohio State University College of Medicine, Columbus, USA.
Eric AltschulerPhysical Medicine and Rehabilitation, Metropolitan Hospital Center, New York, USA.
Inova Fairfax Hospital · USMetropolitan Hospital Center · USThe Ohio State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Good treatments are available for many cases of vertigo due to a peripheral cause such as benign paroxysmal positional vertigo. Conversely, vertigo secondary to a central lesion remains a treatment challenge typically without good pharmacologic or other treatments. We have successfully treated two patients, the first to our knowledge, with central vertigo, one from brain injury, one after stroke, with low dose olanzapine which we found to quickly and dramatically resolve vertigo and permit functional normalization. In our two cases, we found that a low dose of olanzapine 2.5mg daily (typical dosing of olanzapine for the psychiatric disease is 5-20mg daily) caused vertigo to rapidly and dramatically remit. Interestingly, our two cases had different causes and possibly lesion locations.

Indexed as

centralolanzapineperipheraltreatmentvertigo

Identifiers

PMID35237497
PMCPMC8882308
OpenAlexW4214710520

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.