Evidence map›Paper›PMID 35237474›Full record

ArticleCureus2022

Measurement of Quality-of-Life Outcomes in Pediatric and Young Adult Patients Treated for Eosinophilic Esophagitis.

Charles B Chen, Jessica Barry, Praveen K Conjeevaram Selvakumar, Sandra Hong, Lori Mahajan, Sarah Worley, Sophia A Patel

Abstract read
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Charles B ChenPediatric Gastroenterology, University of Missouri, Columbia, USA.
Jessica BarryPediatric Gastroenterology, Hepatology, and Nutrition, Cleveland Clinic Foundation, Cleveland, USA.
Praveen K Conjeevaram SelvakumarPediatric Gastroenterology, Bon Secours Hospital, Richmond, USA.
Sandra HongAllergy and Immunology, Cleveland Clinic Foundation, Cleveland, USA.
Lori MahajanPediatric Gastroenterology, Hepatology, and Nutrition, Cleveland Clinic Foundation, Cleveland, USA.
Sarah WorleyQuantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, USA.
Sophia A PatelPediatric Gastroenterology, Hepatology, and Nutrition, Cleveland Clinic Foundation, Cleveland, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eosinophilic esophagitis is a chronic, immune-mediated esophageal condition that may lead to impairment of quality of life in pediatric and young adult patients. We performed a prospective, cross-sectional study on 40 patients between the ages of 2-21 years with an established diagnosis of eosinophilic esophagitis. The study evaluated physical, emotional, social, and school functioning in patients undergoing treatment with proton pump inhibitors, dietary elimination, or swallowed corticosteroids. There were no statistically significant differences in total or domain-specific quality of life scores between proton pump inhibitors, dietary elimination, and swallowed corticosteroid therapy. Overall, total and domain-specific quality of life were well-preserved in patients with eosinophilic esophagitis, with the highest scores reported in social functioning. There were also no statistically significant associations between clinical, endoscopic, and histologic features and quality-of-life measures.

Indexed as

atopic disorderseosinophilic esophagitispediatricspsychosocial functioningquality of life

Identifiers

PMID35237474
PMCPMC8882214

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.