Evidence map›Paper›PMID 35237454›Full record

ArticleCase reports in hematology2022

An Unusual Case of Multiple Myeloma with Light-Chain Cast Nephropathy Secondary to a Very Large Plasmacytoma without Bone Marrow Involvement.

Justin Komisarof, Jodi Lipof, Joseph DiTursi, Amit Chowdhry, Hae Yoon Grace Choung, W Richard Burack, Louis Constine, Frank Passero

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in hematology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Justin KomisarofDepartment of Medicine, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USA.ORCID https://orcid.org/0000-0002-3591-4625
Jodi LipofDepartment of Hematology and Oncology, Wilmot Cancer Institute, 601 Elmwood Avenue, Rochester, NY 14642, USA.ORCID https://orcid.org/0000-0001-5877-0022
Joseph DiTursiDepartment of Medicine, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USA.
Amit ChowdhryDepartment of Radiation Oncology, Wilmot Cancer Institute, 601 Elmwood Avenue, Rochester, NY 14642, USA.ORCID https://orcid.org/0000-0003-4051-5060
Hae Yoon Grace ChoungDepartment of Pathology and Laboratory Medicine, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USA.
W Richard BurackDepartment of Pathology and Laboratory Medicine, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USA.ORCID https://orcid.org/0000-0002-5584-584X
Louis ConstineDepartment of Radiation Oncology, Wilmot Cancer Institute, 601 Elmwood Avenue, Rochester, NY 14642, USA.ORCID https://orcid.org/0000-0003-0742-1740
Frank PasseroDepartment of Hematology and Oncology, Wilmot Cancer Institute, 601 Elmwood Avenue, Rochester, NY 14642, USA.ORCID https://orcid.org/0000-0001-7428-8826
University of Rochester Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here, we report a case of a patient who presented to Strong Memorial Hospital with new-onset renal failure and anemia and was found to have multiple myeloma with lambda light-chain cast nephropathy secondary to a very large (14 cm × 14 cm × 12 cm) plasmacytoma without bone marrow involvement. This case is notable as solitary plasmacytomas are almost never seen with concomitant myeloma-defining CRAB criteria or significantly elevated serum free light-chain ratios. Although solitary plasmacytomas are typically definitively treated with radiation, this case highlights that systemic treatment may be helpful in certain clinical scenarios.

Identifiers

PMID35237454
PMCPMC8885275
OpenAlexW4212845959

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.