Evidence map›Paper›PMID 35237450›Full record

ReviewJournal of nutrition and metabolism2022

Dyslipidemia Diagnosis and Treatment: Risk Stratification in Children and Adolescents.

Sara Mosca, Graça Araújo, Vanessa Costa, Joana Correia, Anabela Bandeira, Esmeralda Martins, Helena Mansilha, Mónica Tavares, Margarida P Coelho

Open access · goldAbstract readReview
In one paragraph

Review in Journal of nutrition and metabolism, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
12.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 62 citations in OpenAlex.

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  15. [Inappropriate eating habits are associated with hypercholesterolemia in adolescents].Revista medica del Instituto Mexicano del Seguro Social · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Sara MoscaPediatrics Department, Centro Materno-Infantil do Norte, Centro Hospitalar Universitário do Porto, Porto 4050-651, Portugal.ORCID https://orcid.org/0000-0002-5474-7236
Graça AraújoPediatrics Department, Hospital Central do Funchal, Funchal 9000-177, Portugal.ORCID https://orcid.org/0000-0002-2091-6548
Vanessa CostaPediatrics Department, Centro Materno-Infantil do Norte, Centro Hospitalar Universitário do Porto, Porto 4050-651, Portugal.ORCID https://orcid.org/0000-0001-8936-1459
Joana CorreiaReference Center for Inherited Metabolic Disorders, Centro Materno-Infantil do Norte, Centro Hospitalar Universitário do Porto, Porto 4050-651, Portugal.ORCID https://orcid.org/0000-0002-0245-6840
Anabela BandeiraReference Center for Inherited Metabolic Disorders, Centro Materno-Infantil do Norte, Centro Hospitalar Universitário do Porto, Porto 4050-651, Portugal.ORCID https://orcid.org/0000-0003-1203-8180
Esmeralda MartinsReference Center for Inherited Metabolic Disorders, Centro Materno-Infantil do Norte, Centro Hospitalar Universitário do Porto, Porto 4050-651, Portugal.ORCID https://orcid.org/0000-0002-9247-9391
Helena MansilhaPediatric Nutrition Unit, Pediatrics Department, Centro Materno-Infantil do Norte, Centro Hospitalar Universitário do Porto, Porto 4050-651, Portugal.ORCID https://orcid.org/0000-0001-8688-5169
Mónica TavaresPediatric Nutrition Unit, Pediatrics Department, Centro Materno-Infantil do Norte, Centro Hospitalar Universitário do Porto, Porto 4050-651, Portugal.ORCID https://orcid.org/0000-0003-0807-8120
Margarida P CoelhoReference Center for Inherited Metabolic Disorders, Centro Materno-Infantil do Norte, Centro Hospitalar Universitário do Porto, Porto 4050-651, Portugal.ORCID https://orcid.org/0000-0002-6471-4067
Centro Hospitalar do Porto · PTHospital Dr. Nélio Mendonça · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dyslipidemias or dyslipoproteinemias are quantitative changes in total cholesterol concentration, respective fractions, or triglycerides in the plasma. Evidence supported that dyslipidemia in childhood is associated with atherosclerosis in adulthood, and early identification and treatment potentially reduce cardiovascular risk in adulthood, which is the principal cause of morbidity and mortality in developed countries. Dyslipidemias can result from primary lipoprotein metabolism changes due to different genetic causes (primary dyslipidemias) or as a consequence of exogenous factors or other pathologies (secondary dyslipidemias). Therefore, the combined dyslipidemias result from the association of important epigenetic and environmental influences with risk factors for cardiovascular disease. The criterion for lipid metabolism screening at young ages is not widely accepted and possibly follows a universal or directed screening strategy. Additionally, little is known about its long-term effects or possible risk-benefit despite the growing tendency to start pharmacological therapy. Therefore, this study aimed to review the available bibliography on dyslipidemia in pediatric age to present a practical and structured approach to dyslipidemia that focuses on screening, risk stratification for atherosclerotic disease, and therapeutic approach.

Identifiers

PMID35237450
PMCPMC8885266
OpenAlexW4213213155

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.