Evidence map›Paper›PMID 35237449›Full record

ArticleJournal of ophthalmology2022

Choroidal Structural Changes of Posterior Subtenon Triamcinolone Acetonide Injection in Eyes with Refractory Diabetic Macular Edema.

Bing Liu, Guangfeng Ma, Jing Hou, Chenyang Cong

Abstract read
In one paragraph

Article in Journal of ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Switching to subtenon triamcinolone acetonide does not jeopardize the functional and anatomic outcomes of dexamethasone implant treated eyes with diabetic macular edema.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bing LiuDepartment of Ophthalmology, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan 250033, China.ORCID https://orcid.org/0000-0003-3578-1030
Guangfeng MaDepartment of Ophthalmology, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan 250033, China.ORCID https://orcid.org/0000-0003-4595-0408
Jing HouDepartment of Ophthalmology, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan 250033, China.ORCID https://orcid.org/0000-0002-5845-6997
Chenyang CongAffiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250002, China.ORCID https://orcid.org/0000-0003-1107-8949

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo access the choroidal structural changes of posterior subtenon triamcinolone acetonide (PSTA) injection in eyes with refractory diabetic macular edema (DME).

methodsPatients with refractory DME were enrolled and followed for 4 weeks after switching to PSTA injection. All patients underwent spectral-domain optical coherence tomography with enhanced depth imaging, and the choroidal images were binarized into the luminal area and total choroidal area. Subfoveal choroidal thickness (SFCT) and choroidal vascularity index (CVI) were evaluated before and after switching treatments.

resultsAfter switching to PSTA treatment, the final best-corrected visual acuity and central subfield thickness in eyes with refractory DME were significantly improved compared to the baseline values (

conclusionsThe alterations of SFCT and CVI in this study suggest that the choroidal vasculature is involved in the pathogenesis of refractory DME and could be affected by PSTA treatment. SFCT rather than CVI may be a prognostic biomarker for eyes with refractory DME.

Identifiers

PMID35237449
PMCPMC8885276

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