Evidence map›Paper›PMID 35237385›Full record

ArticleOxidative medicine and cellular longevity2022

Orientin Prolongs the Longevity of

Yuan Qu, Lin Shi, Yu Liu, Lv Huang, Huai-Rong Luo, Gui-Sheng Wu

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Miquelianin and spiraeoside fromFrontiers in pharmacology · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yuan QuKey Laboratory for Aging and Regenerative Medicine, Department of Pharmacology School of Pharmacy, Southwest Medical University, Luzhou, Sichuan 646000, China.
Lin ShiKey Laboratory for Aging and Regenerative Medicine, Department of Pharmacology School of Pharmacy, Southwest Medical University, Luzhou, Sichuan 646000, China.
Yu LiuKey Laboratory for Aging and Regenerative Medicine, Department of Pharmacology School of Pharmacy, Southwest Medical University, Luzhou, Sichuan 646000, China.
Lv HuangKey Laboratory for Aging and Regenerative Medicine, Department of Pharmacology School of Pharmacy, Southwest Medical University, Luzhou, Sichuan 646000, China.
Huai-Rong LuoKey Laboratory for Aging and Regenerative Medicine, Department of Pharmacology School of Pharmacy, Southwest Medical University, Luzhou, Sichuan 646000, China.ORCID https://orcid.org/0000-0001-8912-6694
Gui-Sheng WuDepartment of Anesthesiology, Hospital (T.C.M) Affiliated to Southwest Medical University, Luzhou, Sichuan 646000, China.ORCID https://orcid.org/0000-0003-1913-9566
Southwest Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Age is the major risk factor for most of the deadliest diseases. Developing small molecule drugs with antiaging effects could improve the health of aged people and retard the onset and progress of aging-associated disorders. Bioactive secondary metabolites from medicinal plants are the main source for development of medication. Orientin is a water-soluble flavonoid monomer compound widely found in many medicinal plants. Orientin inhibits fat production, antioxidation, and anti-inflammatory activities. In this study, we explored whether orientin could affect the aging of

Indexed as

AMP-Activated Protein KinasesAnimalsAntioxidantsAutophagyCaenorhabditis elegansCaenorhabditis elegans ProteinsDisease Models, AnimalDNA-Binding ProteinsFlavonoidsForkhead Transcription FactorsGlucosidesLongevityNeurodegenerative DiseasesOxidative StressPhytochemicalsPlant ExtractsAMP-Activated Protein KinasesAntioxidantsCaenorhabditis elegans Proteinsdaf-16 protein, C elegansDNA-Binding ProteinsFlavonoidsForkhead Transcription FactorsGlucosidesheat shock factor-1, C elegansorientinPhytochemicalsPlant Extractsskn-1 protein, C elegansTranscription Factors

Identifiers

PMID35237385
PMCPMC8885179
OpenAlexW4213070689

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.