Evidence map›Paper›PMID 35237257›Full record

ArticleFrontiers in immunology2022

Combination of Anti-PD-1 Antibody, Anlotinib and Pegaspargase "Sandwich" With Radiotherapy in Localized Natural Killer/T Cell Lymphoma.

Peng Sun, Yu Wang, Hang Yang, Cui Chen, Man Nie, Xiao-Qing Sun, Xiao-Hua He, Kang-Ming Huang, Jia-Jia Huang, Zhi-Ming Li

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Prognostic value of interim [European radiology · 2025
    Article
  5. Article
  6. Article
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  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Peng SunDepartment of Medical Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, China.
Yu WangDepartment of Medical Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, China.
Hang YangDepartment of Medical Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, China.
Cui ChenDepartment of Oncology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
Man NieDepartment of Medical Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, China.
Xiao-Qing SunDepartment of Medical Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, China.
Xiao-Hua HeDepartment of Medical Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, China.
Kang-Ming HuangDepartment of Medical Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, China.
Jia-Jia HuangDepartment of Medical Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, China.
Zhi-Ming LiDepartment of Medical Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, China.
Sun Yat-sen University · CNSun Yat-sen University Cancer Center · CNState Key Laboratory of Oncology in South China

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Asparaginase/pegaspargase containing regimens combined with radiotherapy are highly effective and considered the cornerstone of localized Natural killer/T-cell lymphoma (NKTL) treatment. However, these chemotherapy regimens inevitably cause relatively high incidence of treatment-related adverse events (TRAEs). Herein we retrospectively evaluated the efficacy and safety of the combined regimen of anti-PD-1 antibody, anlotinib and pegaspargase "sandwich" with radiotherapy in localized NKTL. Anti-PD-1 antibody and pegaspargase at 2500 U/m

Indexed as

AsparaginaseLymphoma, Extranodal NK-T-CellAntineoplastic Combined Chemotherapy ProtocolsDeoxycytidineHumansIndolesKiller Cells, NaturalPolyethylene GlycolsQuinolinesRetrospective StudiesanlotinibAsparaginaseDeoxycytidineIndolespegaspargasePolyethylene GlycolsQuinolinesanlotinibanti-PD-1 antibodynatural killer/T cell lymphomapegaspargaseradiotherapy

Identifiers

PMID35237257
PMCPMC8882643
OpenAlexW4212947378

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.