Evidence map›Paper›PMID 35237238›Full record

ArticleFrontiers in microbiology2021

Transcriptome and Gut Microbiota Profiling Revealed the Protective Effect of Tibetan Tea on Ulcerative Colitis in Mice.

Ning Wang, Tao Wu, Di Du, Jie Mei, Huibo Luo, Zishan Liu, Muhammad Kashif Saleemi, Runhui Zhang, Candace Chang, Muhammad Aamer Mehmood and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 3 countries.

Ning WangCollege of Bioengineering, Sichuan University of Science and Engineering, Zigong, China.
Tao WuSchool of Food and Biological Engineering, Xihua University, Chengdu, China.
Di DuProcess Technology Department, ExxonMobil Research and Engineering, Annandale, NJ, United States.
Jie MeiSichuan Jixiang Tea Co., Ltd., Ya'an, China.
Huibo LuoCollege of Bioengineering, Sichuan University of Science and Engineering, Zigong, China.
Zishan LiuCollege of Bioengineering, Sichuan University of Science and Engineering, Zigong, China.
Muhammad Kashif SaleemiDepartment of Pathology, University of Agriculture, Faisalabad, Pakistan.
Runhui ZhangDepartment of Veterinary Medicine, College of Animal & Veterinary Sciences, Southwest Minzu University, Chengdu, China.
Candace ChangUCLA Microbiome Center, David Geffen School of Medicine at UCLA, Los Angeles, CA, United States.
Muhammad Aamer MehmoodCollege of Bioengineering, Sichuan University of Science and Engineering, Zigong, China.
Hui ZhuCollege of Bioengineering, Sichuan University of Science and Engineering, Zigong, China.
Sichuan University of Science and Engineering · CNExxonMobil (United States) · USGovernment College University, Faisalabad · PKSouthwest Minzu University · CNTea Research Institute · CNUniversity of Agriculture Faisalabad · PKXihua University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traditionally, Ya'an Tibetan tea is routinely consumed by local people in the Tibet region. It is believed to possess promising anti-inflammatory benefits. This study was conducted to elucidate the protective impact of Tibetan tea extract (TTE) on dextran sodium sulfate (DSS)-induced colitis in mice. Mice were split into four groups: control (C) group, Tibetan tea (T) group, DSS-induced model (CD) group, and Tibetan tea + DSS (TD) group. The intake of TTE significantly reduced the clinical symptoms of ulcerative colitis (UC) by alleviating the impact of cellular damage and reducing glandular hypertrophy and the infiltration of inflammatory cells. UC led to a prominent shift of the microbial communities in the gut. Interestingly, the beneficial microbes, such as

Indexed as

gut microbiotaimmune responseRNA-seqTibetan teaulcerative colitis

Identifiers

PMID35237238
PMCPMC8882814
OpenAlexW4212787832

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.