ArticleFrontiers in aging neuroscience2022
Altered Intra- and Inter-Network Connectivity in Drug-Naïve Patients With Early Parkinson's Disease.
Article in Frontiers in aging neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 20 citations in OpenAlex.
- Multi-level static and dynamic graph-theoretical analyses of resting-state functional networks in a Chinese cohort of preterm neonates.iScience · 2026Article
- Early functional network alterations predict motor and cognitive decline in parkinson's disease.Scientific reports · 2025Article
- Aberrant static and dynamic functional network connectivity in patients with noise-induced hearing loss.Quantitative imaging in medicine and surgery · 2025Article
- Motor Functional Hierarchical Organization of Cerebrum and Its Underlying Genetic Architecture in Parkinson's Disease.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Neuroanatomical Insights: Convergence and Divergence of Tinnitus with Normal or Mild Hearing Loss.Biomedicines · 2025Article
- White matter structural changes before and after microvascular decompression for hemifacial spasm.Brain structure & function · 2024Article
- Convergent and divergent intra- and internetwork connectivity in Parkinson's disease with wearing-off.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Article
- Functional reorganization of intranetwork and internetwork connectivity in patients with Ménière's disease.Scientific reports · 2023Article
- Aberrant intra- and internetwork functional connectivity patterns of the anterior and posterior hippocampal networks in schizophrenia.CNS neuroscience & therapeutics · 2023Article
- Normalization effect of dopamine replacement therapy on brain functional connectome in Parkinson's disease.Human brain mapping · 2023Article
Corrections and comments
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Authors and funding
13 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of our study was to investigate differences in whole brain connectivity at different levels between drug-naïve individuals with early Parkinson's disease (PD) and healthy controls (HCs). Resting-state functional magnetic resonance imaging data were collected from 47 patients with early-stage, drug-naïve PD and 50 HCs. Functional brain connectivity was analyzed at the integrity, network, and edge levels; UPDRS-III, MMSE, MOCA, HAMA, and HAMD scores, reflecting the symptoms of PD, were collected for further regression analysis. Compared with age-matched HCs, reduced functional connectivity were mainly observed in the visual (VSN), somatomotor (SMN), limbic (LBN), and deep gray matter networks (DGN) at integrity level [
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