Evidence map›Paper›PMID 35236705›Full record

ArticleBMJ case reports2022

Rare cause of left eye floaters and blurred vision in an immunocompromised patient: acute retinal necrosis (ARN).

Xia Dong, Cleo Wee, Dan Xu, Pengxia Wan

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Xia DongDepartment of Ophthalmology, Sun Yat-sen University First Affiliated Hospital, Guangzhou, Guangdong, China.
Cleo WeeCurtin Medical School, Curtin University Bentley Campus, Perth, Western Australia, Australia.
Dan XuCurtin Medical School, Curtin University Bentley Campus, Perth, Western Australia, Australia daniel.xu@curtin.edu.au wanpengxiadoc@qq.com.ORCID http://orcid.org/0000-0001-6649-1111
Pengxia WanDepartment of Ophthalmology, Sun Yat-sen University First Affiliated Hospital, Guangzhou, Guangdong, China daniel.xu@curtin.edu.au wanpengxiadoc@qq.com.
Sun Yat-sen University · CNCurtin University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute retinal necrosis (ARN) is a clinical syndrome featuring severe vitritis and occlusive vasculitis characterised by full thickness necrotising retinitis. ARN is usually caused by an acute infection by either varicella zoster virus or herpes simplex virus, rarely cytomegalovirus (CMV). ARN often occurs in healthy adults; occasionally affecting immunocompromised patients with poor prognosis including significant visual loss and detachment of the atrophic retina regardless of antiviral treatment. We presented a man in his early 30s with a history of left eye floaters and blurred vision. He was diagnosed with T-cell acute lymphoblastic leukaemia 1 year ago and treated with chemotherapy and allogenic haematopoietic stem cell transplant 5 months ago. His clinical diagnosis was left eye ARN caused by acute viral infection with CMV being the most likely cause, which is rarely seen in immunocompromised patients. Our case highlighted a diagnostic and therapeutic challenge in the absence of guideline or evidence-based literature to follow.

Indexed as

Retinal Necrosis Syndrome, AcuteAntiviral AgentsHerpesvirus 3, HumanHumansImmunocompromised HostMaleVision DisordersVitreous BodyAntiviral Agentsimmunologyinfectious diseasesophthalmologyretina

Identifiers

PMID35236705
PMCPMC8895929
OpenAlexW4214929241

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.