Evidence map›Paper›PMID 35236543›Full record

ArticleOncology research2022

Research Progress in Immunotherapy of NSCLC With EGFR-Sensitive Mutations.

Yudie Yang, Xia Zhang, Yajie Gao, Yan Dong, Di Wang, Yanping Huang, Tianhao Qu, Buqun Fan, Qizheng Li, Chunxia Zhang and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Oncology research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 4 citations in OpenAlex.

  1. Risk prediction of non-small cell lung cancer in patients with pulmonary nodules: a single-center cohort study based on six machine learning algorithms.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Yudie YangDepartment of Oncology, The First Affiliated Hospital of Dalian Medical UniversityDalianP.R. China.
Xia ZhangDepartment of Oncology, Dalian Fifth Peoples HospitalDalianP.R. China.
Yajie GaoDepartment of Oncology, The First Affiliated Hospital of Dalian Medical UniversityDalianP.R. China.
Yan DongDepartment of Oncology, The First Affiliated Hospital of Dalian Medical UniversityDalianP.R. China.
Di WangDepartment of Oncology, The First Affiliated Hospital of Dalian Medical UniversityDalianP.R. China.
Yanping HuangDepartment of Oncology, The First Affiliated Hospital of Dalian Medical UniversityDalianP.R. China.
Tianhao QuDepartment of Oncology, The First Affiliated Hospital of Dalian Medical UniversityDalianP.R. China.
Buqun FanDepartment of Oncology, The First Affiliated Hospital of Dalian Medical UniversityDalianP.R. China.
Qizheng LiDepartment of Oncology, The First Affiliated Hospital of Dalian Medical UniversityDalianP.R. China.
Chunxia ZhangDepartment of Oncology, The First Affiliated Hospital of Dalian Medical UniversityDalianP.R. China.
Xiaonan CuiDepartment of Oncology, The First Affiliated Hospital of Dalian Medical UniversityDalianP.R. China.
Bin ZhangDepartment of Oncology, The First Affiliated Hospital of Dalian Medical UniversityDalianP.R. China.
First Affiliated Hospital of Dalian Medical University · CNDalian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer is a malignant tumor with high incidence and mortality across the world. The use of immune checkpoint inhibitors for lung cancer has improved the prognosis of some lung cancer patients to a greater extent and provided a new direction for the clinical treatment of lung cancer. Immunotherapy still has limitations in terms of its appropriate population and adverse reactions. Particularly for non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutation, there has been no major breakthrough in current immunotherapy. Whether immunotherapy can bring new benefits after drug resistance is induced by tyrosine kinase inhibitor-targeted therapy and whether the combination of immunotherapy with other treatments can improve the prognosis remain to be studied in depth. In this article, we provide a detailed review of the relevant characteristics of the tumor microenvironment of NSCLC with EGFR mutation and the current research on immunotherapy for NSCLC with EGFR mutation.

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsErbB ReceptorsHumansImmunotherapyMutationTumor MicroenvironmentEGFR protein, humanErbB Receptors

Identifiers

PMID35236543
PMCPMC9110674
OpenAlexW4214897068

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.