ReviewArthroplasty (London, England)2020
Risk factors affect success rate of debridement, antibiotics and implant retention (DAIR) in periprosthetic joint infection.
Review in Arthroplasty (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- The role of the gastrocnemius flap in implant retention strategies for acute periprosthetic joint infection following total knee arthroplasty: a systematic review.Archives of orthopaedic and trauma surgery · 2026Pooled it
- Success rate of single versus multiple debridement, antibiotics, and implant retention (DAIR) in hip and knee periprosthetic joint infection: a systematic review and meta-analysis.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024Pooled it
- DVIA technique for acute periprosthetic joint infection: a surgical technique and case series.Arthroplasty (London, England) · 2026Article
- Antibiotic-loaded calcium sulphate beads in in debridement, antibiotics, and implant retention (DAIR) for acute hip and knee periprosthetic joint infection: a retrospective comparative cohort study.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026Article
- Debridement, Antibiotics and Implant Retention in the Management of Periprosthetic Joint Infection: One-Year Outcomes, Epidemiology and Predictors of Failure.Journal of clinical medicine · 2026Article
- Type of acute periprosthetic joint infection may not affect failure of debridement, antibiotics, and implant retention after total knee arthroplasty.Journal of bone and joint infection · 2025Article
- Investigating the Translational Value of Periprosthetic Joint Infection Models to Determine the Risk and Severity of Staphylococcal Biofilms.ACS infectious diseases · 2024Article
- DAIR for periprosthetic joint infections-One week to save the joint?Arthroplasty (London, England) · 2024Article
- Antiseptics' Concentration, Combination, and Exposure Time on Bacterial and Fungal Biofilm Eradication.Arthroplasty today · 2024Article
- Impact of unplanned second debridement, antibiotics and implant retention on long-term outcomes in knee exchange arthroplasty: Elevated risk of failure and reinfection.Journal of experimental orthopaedics · 2024Article
- Investigating the translational value of Periprosthetic Joint Infection (PJI) models to determine the risk and severity of Staphylococcal biofilms.bioRxiv : the preprint server for biology · 2024Article
- Fellowship Training in Arthroplasty Improves Treatment Success of Debridement, Antibiotics, and Implant Retention for Periprosthetic Knee Infections.Arthroplasty today · 2024Article
- What to Know about Antimicrobial Coatings in Arthroplasty: A Narrative Review.Medicina (Kaunas, Lithuania) · 2024Review
- Cathodic voltage-controlled electrical stimulation and betadine decontaminate nosocomial pathogens from implant surfaces.mSphere · 2024Article
- Rare Pseudotumor in Ceramic-On-Ceramic Total Hip Replacement with Concomitant Fungal Periprosthetic Joint Infection: A Case Report.The American journal of case reports · 2023Article
- Debridement, Antibiotics and Implant Retention: A Systematic Review of Strategies for Treatment of Early Infections after Revision Total Knee Arthroplasty.Journal of clinical medicine · 2023Review
- Do Antibiotic-Loaded Calcium Sulfate Beads Improve Outcomes After Debridement, Antibiotics, and Implant Retention? A Matched Cohort Study.Arthroplasty today · 2022Article
- Standardized quantification of biofilm in a novel rabbit model of periprosthetic joint infection.Journal of bone and joint infection · 2022Article
- Deep infection after hip hemiarthroplasty: risk factors for infection and outcome of treatments.Bone & joint open · 2021Article
- A Short-Course Antibiotic Prophylaxis Is Associated with Limited Antibiotic Resistance Emergence in Post-Operative Infection of Pelvic Primary Bone Tumor Resection.Antibiotics (Basel, Switzerland) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPeriprosthetic joint infection (PJI) is the most devastating complication of joint replacement that seriously affects the quality of life and causes a heavy burden to the families and society. Due to shorter hospital stays, lower costs, improved joint function and less morbidity, a process of debridement, antibiotics and implant retention (DAIR) is recommended as the preferred treatment for acute periprosthetic joint infection. However, the factors that impact the success rate of DAIR remain controversial. This article evaluates the influential factors of DAIR and provides insights for orthopaedics surgeons to make optimal decisions to improve the success rate of DAIR.
conclusionThe poor general condition of patients, high preoperative C-reactive protein (CRP) level, repeated joint surgeries, and Methicillin-resistant Staphylococcus aureus (MRSA) infections may be associated with lower DAIR success rate. To the contrary, early surgery, radical debridement, exchange of removable components, washing with iodine and vacuum sealing drainage (VSD) may improve the success rate of DAIR. A sinus tract may not be absolutely contraindicated, but surgeons should treat it with caution. As there is no consensus on many issues, more high-quality research is required.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.