Evidence map›Paper›PMID 35236353›Full record

Trial reportBMC medicine2022

Promoting deceased organ and tissue donation registration in family physician waiting rooms (RegisterNow-1): a pragmatic stepped-wedge, cluster randomized controlled registry trial.

Alvin Ho-Ting Li, Amit X Garg, Jeremy M Grimshaw, Versha Prakash, Alexie J Dunnett, Stephanie N Dixon, Monica Taljaard, Joanna Mitchell, Kyla L Naylor, Cathy Faulds and 13 more

Registry-linked trialOpen access · goldAbstract readRandomized Controlled TrialPragmatic Clinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03213171 (Promoting Organ and Tissue Donation Registration in Family Physician Offices), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03213171 nacompletednot on this map

Promoting Organ and Tissue Donation Registration in Family Physician Offices: a Pragmatic Stepped-wedge Cluster Randomized Controlled Registry Trial (RegisterNow Trial)

TypeinterventionalSponsorLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sRan2017 to 2019Enrolled6ConditionsOrgan Donation, Registration for Deceased Organ DonationArmsReception staff providing handout., Mobile Tablet (e.g. iPad)
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 9 institutions in 2 countries.

Alvin Ho-Ting LiClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada. ali66@uwo.ca.
Amit X GargLawson Health Research Institute, London, ON, Canada.
Jeremy M GrimshawClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Versha PrakashTrillium Gift of Life Network, Toronto, ON, Canada.
Alexie J DunnettLawson Health Research Institute, London, ON, Canada.
Stephanie N DixonLawson Health Research Institute, London, ON, Canada.
Monica TaljaardClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Joanna MitchellCitizen partner, London, ON, Canada.
Kyla L NaylorInstitute for Clinical Evaluative Sciences (ICES) Western, London, ON, Canada.
Cathy FauldsDepartment of Family Medicine, Western University, London, ON, Canada.
Rachel BevanDepartment of Family Medicine, Western University, London, ON, Canada.
Leah GetchellLawson Health Research Institute, London, ON, Canada.
Greg KnollClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
S Joseph KimUniversity Health Network, University of Toronto, Toronto, ON, Canada.
Jessica SontropLawson Health Research Institute, London, ON, Canada.
Allison TongSydney School of Public Health, University of Sydney, Sydney, NSW, Australia.
Lise M BjerreSchool of Epidemiology and Public Health, University of Ottawa, Ottawa, ON, Canada.
Karyn HyjekTrillium Gift of Life Network, Toronto, ON, Canada.
Donna CurrieCitizen partner, London, ON, Canada.
Susan EdwardsCitizen partner, London, ON, Canada.
Mike SullivanCitizen partner, London, ON, Canada.
Linda Harvey-RiouxCitizen partner, London, ON, Canada.
Justin PresseauClinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
University of Ottawa · CAWestern University · CALawson Health Research Institute · CATrillium Therapeutics (Canada) · CAInstitute for Clinical Evaluative Sciences · CAOttawa Hospital · CAOttawa Hospital Research InstituteUniversity Health Network · CAUniversity of Sydney · AU

Funding

CIHR CIHR-SCT-151609
6 · The paper itself

Abstract

backgroundThe shortage of available organs for life-saving transplants persists worldwide. While a majority support donating their organs or tissue when they die, many have not registered their wish to do so. When registered, next of kin are much more likely to follow-through with the decision to donate. In many countries, most people visit their family physician office each year and this setting is a promising, yet underused, site where more people could register for deceased organ donation. Our primary aim was to evaluate the effectiveness of an intervention to promote organ donation registration in family physician's offices.

methodsWe developed an intervention to address barriers and enablers to organ donation registration that involved physician office reception staff inviting patients to register on a tablet in the waiting room while they waited for their appointment. We conducted a cross-sectional stepped-wedge cluster randomized controlled registry trial to evaluate the intervention. We recruited six family physician offices in Canada. All offices began with usual care and then every two weeks, one office (randomly assigned) started the intervention until all offices delivered the intervention. The primary outcome was registration for deceased organ donation in the provincial organ registration registry, assessed within the 7 days of the physician visit. At the end of the trial, we also conducted interviews with clinic staff to assess any barriers and enablers to delivering the intervention.

resultsThe trial involved 24,616 patient visits by 13,562 unique patients: 12,484 visits in the intervention period and 12,132 in the control period. There was no statistically significant difference in the percentage of patients registered for deceased organ donation in the intervention versus control period (48.0% vs 46.2%; absolute difference after accounting for the secular trend: 0.12%; 95% CI: - 2.30, 2.54; p=0.92). Interviews with clinic staff indicated location of the tablet within a waiting room, patient rapport, existing registration, confidence and motivation to deliver the intervention and competing priorities as barriers and enablers to delivery.

conclusionsOur intervention did not increase donor registration. Nonetheless, family physician offices may still remain a promising setting to develop and evaluate better interventions to increase organ donation registration.

trial registrationNCT03213171.

Indexed as

Physicians, FamilyTissue and Organ ProcurementCross-Sectional StudiesHumansRegistriesWaiting RoomsBehaviour change techniquesCluster randomized trialFamily physician officesOrgan donationOrgan registrationPragmatic trialStepped-wedge trial

Identifiers

PMID35236353
PMCPMC8892727
OpenAlexW4214947486

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.