ArticleBMC cancer2022
Incidence and survival in oral and pharyngeal cancers in Finland and Sweden through half century.
Article in BMC cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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13 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- The duration of intervals on the oral cancer care pathway and implications for survival: a systematic review and meta-analysis.Frontiers in public health · 2023Pooled it
- Peritonsillar abscess as a clinical sign of oropharyngeal cancer - a Swedish national cohort study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Improvement in Survival Rates and Quality of Life Among Patients Surgically Treated for Squamous Cell Carcinoma of the Oral Cavity.Journal of maxillofacial and oral surgery · 2026Article
- Overall survival and prognostic factors of oral cavity and oropharyngeal squamous cell carcinomas in Saudi Arabia: a population-based cohort study (2000-2019).Frontiers in oncology · 2026Article
- Epidemiology of Oral Cancer in Cyprus: A Population-Based Cancer Registry Study and Policy Implications.Cureus · 2025Article
- Detection and significance of HPV16 E5-specific productive transcripts in oropharyngeal carcinoma.BMC cancer · 2025Article
- Global, Regional, and National Burden of Pharyngeal Cancer and Projections to 2050 in 185 Countries: A Population-Based Systematic Analysis of GLOBOCAN 2022.Journal of Korean medical science · 2025Article
- Intracellular bacterial LPS drives pyroptosis and promotes aggressive phenotype in oral squamous cell carcinoma.Medical oncology (Northwood, London, England) · 2025Article
- LINC02154 promotes cell cycle and mitochondrial function in oral squamous cell carcinoma.Cancer science · 2025Article
- Imaging-based evaluation of cervical muscle mass and 6-month survival in males with hypopharyngeal carcinoma.Acta oncologica (Stockholm, Sweden) · 2024Article
- Altered oral microbiome, but normal human papilloma virus prevalence in cartilage-hair hypoplasia patients.Orphanet journal of rare diseases · 2024Article
- Article
- Post-Treatment Neck Dissection of Tonsillar and Base of Tongue Squamous Cell Carcinoma in the Era of PET-CT, HPV, and p16.Viruses · 2022Article
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Authors and funding
4 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCancers of the oral cavity and pharynx encompass a heterogeneous group of cancers for which known risk factors include smoking, alcohol consumption and human papilloma virus (HPV) infection but their influence is site-specific with HPV mainly influencing oropharyngeal cancer. Their incidence and survival rates are not well known over extended periods of time. PATIENTS/
methodsData were obtained for Finnish (FI) and Swedish (SE) patients from the Nordcan database recently updated through 2019. Age-adjusted incidence trends (FI from 1953, SE from 1960) and relative survival rates for years 1970 through 2019 were calculated.
resultsWe observed a prominent increase in oral and oropharyngeal cancers in FI and SE men and women but the trend for oral cancer was interrupted for SE men in 1985 and possibly also for FI and SE women in 2015. The trend changes in male and female oral cancer was confirmed in data for Denmark and Norway. Relative survival for these cancers has improved overall but they differed for one cluster of oral, oropharyngeal and nasopharyngeal cancers with 60-70% 5-year survival in the last period and hypopharyngeal cancer with 25% male survival. In all these cancers, survival for old patients was unfavorable. DISCUSSION/
conclusionWe hypothesize that reduction in smoking prevalence helped to stop the increase in oral cancer especially in men. As the prevalence of smoking is decreasing, HPV is becoming a dominant risk factor, particularly for the increasing oropharyngeal cancer. Prevention needs to emphasize sexual hygiene and HPV vaccination.
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