Evidence map›Paper›PMID 35236011›Full record

ArticleThe European journal of neuroscience2022

Inhibitory inputs to an inhibitory interneuron: Spontaneous postsynaptic currents and GABA

Pablo Beltrán-Matas, Áurea Castilho, Barbora Tencer, Margaret L Veruki, Espen Hartveit

Open access · hybridAbstract read
In one paragraph

Article in The European journal of neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Functional properties of GABAFrontiers in ophthalmology · 2023
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Pablo Beltrán-MatasDepartment of Biomedicine, University of Bergen, Bergen, Norway.ORCID 0000-0003-3817-5095
Áurea CastilhoDepartment of Biomedicine, University of Bergen, Bergen, Norway.ORCID 0000-0001-7012-5915
Barbora TencerDepartment of Biomedicine, University of Bergen, Bergen, Norway.ORCID 0000-0003-0685-9679
Margaret L VerukiDepartment of Biomedicine, University of Bergen, Bergen, Norway.ORCID 0000-0002-0532-144X
Espen HartveitDepartment of Biomedicine, University of Bergen, Bergen, Norway.ORCID 0000-0003-1798-1901
University of Bergen · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amacrine cells constitute a large and heterogeneous group of inhibitory interneurons in the retina. The A17 amacrine plays an important role for visual signalling in the rod pathway microcircuit of the mammalian retina. It receives excitatory input from rod bipolar cells and provides feedback inhibition to the same cells. However, from ultrastructural investigations, there is evidence for input to A17s from other types of amacrine cells, presumably inhibitory, but there is a lack of information about the identity and functional properties of the synaptic receptors and how inhibition contributes to the integrative properties of A17s. Here, we studied the biophysical and pharmacological properties of GABAergic spontaneous inhibitory postsynaptic currents (spIPSCs) and GABA

Indexed as

Amacrine CellsReceptors, GABA-AAnimalsgamma-Aminobutyric AcidInhibitory Postsynaptic PotentialsMammalsPatch-Clamp TechniquesRatsRetinaRetinal Rod Photoreceptor Cellsgamma-Aminobutyric AcidReceptors, GABA-AA17 amacrineGABAA receptorsretinal circuitryrod pathwaysynaptic transmission

Identifiers

PMID35236011
PMCPMC9314042
OpenAlexW4214844693

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.