ArticleJournal of pain and symptom management2022
HIV Symptom Clusters are Similar Using the Dimensions of Symptom Occurrence and Distress.
Article in Journal of pain and symptom management, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Exploring psychological symptom associations among people living with HIV using an apriori algorithm.BMC infectious diseases · 2026Article
- Cytokine-Cytokine Receptor Interaction and Endocytosis are Common Pathways for Symptom Burden and Sickness Behavior Symptoms in Oncology Patients Undergoing Chemotherapy.Cancer medicine · 2025Article
- Profiles of HIV/AIDS stigma and psychological well-being in relation to embodiment among people living with HIV.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- State of the "Art" in Precision Health Symptom Science Research.Seminars in oncology nursing · 2025Review
- Differences in symptom clusters based on multidimensional symptom experience and symptom burden in stroke patients.Scientific reports · 2025Article
- Impact of Multimorbidity on Symptom Burden and Symptom Clusters in Patients Receiving Chemotherapy.Cancer medicine · 2025Article
- Psychometric characteristics of the Spanish version of the HIV Symptom Index.Journal of patient-reported outcomes · 2024Observational
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
contextPeople living with HIV infection (PLWH) in the United States continue to experience a high symptom burden despite improvements in antiretroviral therapy.
objectivesThe purpose of this study was to determine if the number and types of symptom clusters differed based on whether symptom occurrence rates or distress ratings were used to create the clusters.
methodsData from 2,000 patients with complete symptom occurrence rates and distress scores on the 20-item HIV Symptom Index from their first ambulatory clinic visit at one of six national HIV centers of excellence in the Center for AIDS Research Network of Integrated Clinical Systems were used in these analyses. Exploratory factor analysis was used to create the symptom clusters.
resultsThe same four symptom clusters (i.e., gastrointestinal, psychological, pain, body image) were identified using occurrence rates and distress ratings. For both dimensions of the symptom experience, the psychological, pain, and body image clusters each had the same symptoms. For the gastrointestinal cluster, four symptoms loaded on the occurrence dimension and six symptoms loaded on the distress dimension.
conclusionThe number and types of symptom clusters were relatively similar across the occurrence and distress dimensions of the symptom experience. Symptom clusters in PLWH may provide insights into the development of targeted interventions for multiple co-occurring symptoms.
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