Evidence map›Paper›PMID 35235813›Full record

SynthesisThe American journal of the medical sciences2022

A clinical profile of infective endocarditis in patients with recent COVID-19: A systematic review.

Juan A Quintero-Martinez, Joya-Rita Hindy, Maryam Mahmood, Danielle J Gerberi, Daniel C DeSimone, Larry M Baddour

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in The American journal of the medical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
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  7. COVID-19-associated MRSA infective endocarditis and mitral valve perforation: a case report.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2023
    Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Juan A Quintero-MartinezDivision of Infectious Diseases, Departments of Medicine and Cardiovascular Diseases, Mayo Clinic College of Medicine and Science, Rochester, MN, USA. Electronic address: quinteromartinez.juan@mayo.edu.
Joya-Rita HindyDivision of Infectious Diseases, Departments of Medicine and Cardiovascular Diseases, Mayo Clinic College of Medicine and Science, Rochester, MN, USA.
Maryam MahmoodDivision of Infectious Diseases, Departments of Medicine and Cardiovascular Diseases, Mayo Clinic College of Medicine and Science, Rochester, MN, USA.
Danielle J GerberiMayo Clinic Libraries, Mayo Clinic, Rochester, MN, USA.
Daniel C DeSimoneDivision of Infectious Diseases, Departments of Medicine and Cardiovascular Diseases, Mayo Clinic College of Medicine and Science, Rochester, MN, USA.
Larry M BaddourDivision of Infectious Diseases, Departments of Medicine and Cardiovascular Diseases, Mayo Clinic College of Medicine and Science, Rochester, MN, USA.
Mayo Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCoronavirus disease 2019 (COVID-19) can progress to cardiovascular complications which are linked to higher in-hospital mortality rates. Infective endocarditis (IE) can develop in patients with recent COVID-19 infections, however, characterization of IE following COVID-19 infection has been lacking. To better characterize this disease, we performed a systematic review with descriptive analysis of the clinical features and outcomes of these patients.

methodsOur search was conducted in 8 databases for all published reports of probable or definite IE in patients with a prior COVID-19 confirmed diagnosis. After ensuring an appropriate inclusion of the articles, we extracted data related to clinical characteristics, modified duke criteria, microbiology, outcomes, and procedures.

resultsSearches generated a total of 323 published reports, and 20 articles met our inclusion criteria. The mean age of patients was 52.2 ± 16.9 years and 76.2% were males. Staphylococcus aureus was isolated in 8 (38.1%) patients, Enterococcus faecalis in 3 patients (14.3%) and Streptococcus mitis/oralis in 2 (9.5%) patients. The mean time interval between COVID-19 and IE diagnoses was 16.7 ± 15 days. Six (28.6%) patients required critical care due to IE, 7 patients (33.3%) underwent IE-related cardiac surgery and 5 patients (23.8%) died during their IE hospitalization.

conclusionsOur systematic review provides a profile of clinical features and outcomes of patients with a prior COVID-19 infection diagnosis who subsequently developed IE. Due to the ongoing COVID-19 pandemic, it is essential that clinicians appreciate the possibility of IE as a unique complication of COVID-19 infection.

Indexed as

COVID-19EndocarditisEndocarditis, BacterialStaphylococcal InfectionsAdultAgedFemaleHumansMaleMiddle AgedPandemicsRetrospective StudiesCOVID-19Infective endocarditisOutcomesSARS-CoV-2

Identifiers

PMID35235813
PMCPMC8882249
OpenAlexW4214664729

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.