Evidence map›Paper›PMID 35235812›Full record

ArticleThe American journal of the medical sciences2022

Profile trends of non-COVID patients admitted to the cardiac intensive care unit during the 2020 COVID pandemic.

Ofir Koren, Moriah Shachar, Amit Shahar, Mohammad Barbour, Ehud Rozner, Daniel Benhamou, Alisa Leeds Rosenberg, Yoav Turgeman, Robert Naami, Edmund Naami and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of the medical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Ofir KorenHeart Institute, Emek Medical Center, Afula, Israel; Bruce Rappaport Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel. Electronic address: Ofirko1@clalit.org.il.
Moriah ShacharThe Azrieli Faculty of Medicine, Bar-Ilan University, Zefat, Israel.
Amit ShaharBruce Rappaport Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel.
Mohammad BarbourHeart Institute, Emek Medical Center, Afula, Israel.
Ehud RoznerHeart Institute, Emek Medical Center, Afula, Israel.
Daniel BenhamouBruce Rappaport Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel.
Alisa Leeds RosenbergBiology Faculty, Pepperdine University, Malibu, CA, USA.
Yoav TurgemanHeart Institute, Emek Medical Center, Afula, Israel; Bruce Rappaport Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel.
Robert NaamiInternal Medicine, University Hospitals Cleveland Medical Center, Cleveland, USA.
Edmund NaamiSchool of Medicine, University of Illinois, Chicago, USA.
Einat MaderIntegrative Medicine Service, Emek Medical Center, Afula, Israel; Bruce Rappaport Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel.
Saleem Abu RajabInternal Medicine C, Emek Medical Center, Afula, Israel.
Emek Medical Center · ILTechnion – Israel Institute of Technology · ILBar-Ilan University · ILPepperdine University · USUniversity Hospitals of Cleveland · USUniversity of Illinois Chicago · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDuring the COVID-19 outbreak, numerous reports indicated a higher mortality rate among cardiovascular patients. We investigated how this trend applied to patients admitted to the cardiac intensive care unit (CICU).

methodsWe retrospectively compared CICU patients admitted during the initial peak of the COVID outbreak between February and May 2020 (Covid Era, CE group) to a control group in pre-pandemic time in 2019. We interviewed patients to determine the symptom onset time and the time interval between symptomology and hospital arrival.

resultsThe data of 292 patients were used in the analysis (119 patients in the CE group and 173 in the control group). CE patients had a higher incidence of ischemic heart disease (IHD) (p<.03), heart failure (p<.04), and psychiatric disorders (p<.001). During COVID time, more patients were hospitalized with myocarditis (OR: 26.45), arrhythmias (OR: 2.88), and new heart failure (HF) (p<.001) and less with STEMI (OR: 0.39; 95% CI: 0.24-0.63). Fewer PCIs were performed in the CE group (p<.001), with an overall lower success rate (p<.05) than reported in the control group. Patients in the CE group reported a longer period between symptom onset to hospital arrival (p<.001, χ2 = 12.42). The six-month survival rate was significantly lower in CE patients (χ2 = 7.01, P = 0.008).

conclusionsAmong CICU patients admitted to our center during the initial period of the COVID pandemic, STEMI events were less frequent while cases of newly diagnosed HF sharply increased. Patients waited longer after symptom onset before seeking medical care during the pandemic. The delay may have resulted in clinical deterioration that could explain the high mortality rate and the new HF admission rate.

Indexed as

COVID-19Heart FailureST Elevation Myocardial InfarctionHospital MortalityHumansIntensive Care UnitsPandemicsRetrospective StudiesCardiac intensive care unitCovid-19

Identifiers

PMID35235812
PMCPMC8882251
OpenAlexW4214494165

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.