ReviewPlant physiology2021
Transport, functions, and interaction of calcium and manganese in plant organellar compartments.
Review in Plant physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed, 86 citations in OpenAlex.
- Gdt1, Gdt2 and the P-type ATPase Pmr1 regulate divalent cations (Ca²⁺ and Mn²⁺) in the fission yeast Schizosaccharomyces pombe.International microbiology : the official journal of the Spanish Society for Microbiology · 2026Article
- Comparative Transcriptomic Analysis Reveals Conserved and Nutrient-Specific Responses to Nutrient Deficiencies in Quinoa.Plants (Basel, Switzerland) · 2026Article
- Manganese Oxidation during Vegetation Burning.Environmental science & technology · 2026Article
- Health risk assessment and ionomic profiling under cadmium, lead, zinc, and manganese stress in Amaranthus cruentus.BMC plant biology · 2026Article
- Effects of Subchronic Manganese and Iron Exposure, Alone or in Combination, on Elemental Distribution in Rats.Biological trace element research · 2025Article
- Transcriptomic and physiological analyses revealed nicotianamine enhances wheat tolerance to excess manganese.iScience · 2025Article
- Removal of Toxic Metabolites-Chelation: Manganese Disorders.Journal of inherited metabolic disease · 2025Review
- A comparative study ofPhysiology and molecular biology of plants : an international journal of functional plant biology · 2025Article
- Inter-Organellar CaCells · 2025Review
- Temporal dynamics of medium and micronutrient requirements in Epimedium pubescens: key elements regulating growth and Icariin-Flavonoids biosynthesis.BMC plant biology · 2025Article
- Transformation of flg22 perception into electrical signals decoded in vasculature leads to sieve tube blockage and pathogen resistance.Science advances · 2025Article
- Article
- Manganese handling in plants: Advances in the mechanistic and functional understanding of transport pathways.Quantitative plant biology · 2025Review
- Interactive effects of combined manganese and microplastic pollution on soybean growth.Frontiers in plant science · 2025Article
- Golgi apparatus-localized CATION CALCIUM EXCHANGER4 promotes osmotolerance of Arabidopsis.Plant physiology · 2024Article
- Silicon regulation of manganese homeostasis in plants: mechanisms and future prospective.Frontiers in plant science · 2024Review
- RNA editing events and expression profiles of mitochondrial protein-coding genes in the endemic and endangered medicinal plant,Frontiers in plant science · 2024Article
- AnPlant signaling & behavior · 2023Article
- Manganese regulation of COPII condensation controls circulating lipid homeostasis.Nature cell biology · 2023Article
- Metabolic Responses to Manganese Toxicity in Soybean Roots and Leaves.Plants (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Calcium (Ca2+) and manganese (Mn2+) are essential elements for plants and have similar ionic radii and binding coordination. They are assigned specific functions within organelles, but share many transport mechanisms to cross organellar membranes. Despite their points of interaction, those elements are usually investigated and reviewed separately. This review takes them out of this isolation. It highlights our current mechanistic understanding and points to open questions of their functions, their transport, and their interplay in the endoplasmic reticulum (ER), vesicular compartments (Golgi apparatus, trans-Golgi network, pre-vacuolar compartment), vacuoles, chloroplasts, mitochondria, and peroxisomes. Complex processes demanding these cations, such as Mn2+-dependent glycosylation or systemic Ca2+ signaling, are covered in some detail if they have not been reviewed recently or if recent findings add to current models. The function of Ca2+ as signaling agent released from organelles into the cytosol and within the organelles themselves is a recurrent theme of this review, again keeping the interference by Mn2+ in mind. The involvement of organellar channels [e.g. glutamate receptor-likes (GLR), cyclic nucleotide-gated channels (CNGC), mitochondrial conductivity units (MCU), and two-pore channel1 (TPC1)], transporters (e.g. natural resistance-associated macrophage proteins (NRAMP), Ca2+ exchangers (CAX), metal tolerance proteins (MTP), and bivalent cation transporters (BICAT)], and pumps [autoinhibited Ca2+-ATPases (ACA) and ER Ca2+-ATPases (ECA)] in the import and export of organellar Ca2+ and Mn2+ is scrutinized, whereby current controversial issues are pointed out. Mechanisms in animals and yeast are taken into account where they may provide a blueprint for processes in plants, in particular, with respect to tunable molecular mechanisms of Ca2+ versus Mn2+ selectivity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.