Evidence map›Paper›PMID 35235439›Full record

ArticleJournal of neurophysiology2022

Proactive inhibition is marked by differences in the pattern of motor cortex activity during movement preparation and execution.

Vishal Rawji, Sachin Modi, Lorenzo Rocchi, Marjan Jahanshahi, John C Rothwell

Open access · hybridAbstract read
In one paragraph

Article in Journal of neurophysiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Cortically Evoked Movement in Humans Reflects History of Prior Executions, Not Plan for Upcoming Movement.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Vishal RawjiDepartment of Clinical and Movement Neurosciences, University College London Queen Square Institute of Neurology, London, United Kingdom.ORCID 0000-0001-7291-0204
Sachin ModiDepartment of Clinical and Movement Neurosciences, University College London Queen Square Institute of Neurology, London, United Kingdom.
Lorenzo RocchiDepartment of Clinical and Movement Neurosciences, University College London Queen Square Institute of Neurology, London, United Kingdom.
Marjan JahanshahiDepartment of Clinical and Movement Neurosciences, University College London Queen Square Institute of Neurology, London, United Kingdom.
John C RothwellDepartment of Clinical and Movement Neurosciences, University College London Queen Square Institute of Neurology, London, United Kingdom.
National Hospital for Neurology and Neurosurgery · GBUniversity of Cagliari · IT

Funding

UKRI | Medical Research Council (MRC) MR/K501268/1
6 · The paper itself

Abstract

Successful human behavior relies on the ability to flexibly alter movements depending on the context in which they are made. One such context-dependent modulation is proactive inhibition, a type of behavioral inhibition used when anticipating the need to stop or change movements. We investigated how the motor cortex might prepare and execute movements made under different contexts. We used transcranial magnetic stimulation (TMS) in different coil orientations [postero-anterior (PA) and antero-posterior (AP) flowing currents] and pulse widths (120 and 30 µs) to probe the excitability of different inputs to corticospinal neurons while participants performed two reaction time tasks: a simple reaction time task and a stop-signal task requiring proactive inhibition. We took inspiration from state space models to assess whether the pattern of motor cortex activity changed due to proactive inhibition (PA and AP neuronal circuits represent the

Indexed as

Motor CortexElectromyographyEvoked Potentials, MotorHumansMovementProactive InhibitionReaction TimeTranscranial Magnetic Stimulationdynamical systemsmotor controlproactive inhibitiontranscranial magnetic stimulation

Identifiers

PMID35235439
PMCPMC8957347
OpenAlexW4214947715

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.