Evidence map›Paper›PMID 35235350›Full record

ArticleScience advances2022

Mechanistic basis of choline import involved in teichoic acids and lipopolysaccharide modification.

Natalie Bärland, Anne-Stéphanie Rueff, Gonzalo Cebrero, Cedric A J Hutter, Markus A Seeger, Jan-Willem Veening, Camilo Perez

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Natalie BärlandBiozentrum, University of Basel, Basel 4056, Switzerland.ORCID 0000-0002-8168-6248
Anne-Stéphanie RueffDepartment of Fundamental Microbiology, Faculty of Biology and Medicine, University of Lausanne, Lausanne 1015, Switzerland.
Gonzalo CebreroBiozentrum, University of Basel, Basel 4056, Switzerland.ORCID 0000-0001-7171-0921
Cedric A J HutterInstitute of Medical Microbiology, University of Zurich, Zurich, Switzerland.ORCID 0000-0002-8920-3343
Markus A SeegerInstitute of Medical Microbiology, University of Zurich, Zurich, Switzerland.ORCID 0000-0003-1761-8571
Jan-Willem VeeningDepartment of Fundamental Microbiology, Faculty of Biology and Medicine, University of Lausanne, Lausanne 1015, Switzerland.ORCID 0000-0002-3162-6634
Camilo PerezBiozentrum, University of Basel, Basel 4056, Switzerland.ORCID 0000-0002-5800-0084
University of Basel · CHUniversity of Lausanne · CHUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phosphocholine molecules decorating bacterial cell wall teichoic acids and outer-membrane lipopolysaccharide have fundamental roles in adhesion to host cells, immune evasion, and persistence. Bacteria carrying the operon that performs phosphocholine decoration synthesize phosphocholine after uptake of the choline precursor by LicB, a conserved transporter among divergent species.

Indexed as

LipopolysaccharidesTeichoic AcidsCholineCryoelectron MicroscopyMembrane Transport ProteinsPhosphorylcholineStreptococcus pneumoniaeCholineLipopolysaccharidesMembrane Transport ProteinsPhosphorylcholineTeichoic Acids

Identifiers

PMID35235350
PMCPMC8890701
OpenAlexW4220792590

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.