Evidence map›Paper›PMID 35235084›Full record

ArticleCancer causes & control : CCC2022

Healthy lifestyle index and risk of pancreatic cancer in the Women's Health Initiative.

Rita Peila, Mace Coday, Tracy E Crane, Nazmus Saquib, Aladdin H Shadyab, Fred K Tabung, Xiaochen Zhang, Jean Wactawski-Wende, Thomas E Rohan

Erratum issuedOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer causes & control : CCC, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 17 citations in OpenAlex.

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  13. Association Between the Healthy Lifestyle Index and Risk of Multimorbidity in the Women's Health Initiative.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 2 countries.

Rita PeilaDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY, 10461, USA. rita.peila@einsteinmed.org.
Mace CodayDepartment of Preventive Medicine, College of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
Tracy E CraneBehavioral Measurement and Interventions Cancer Prevention and Control Program, University of Arizona, Tucson, AZ, USA.
Nazmus SaquibCollege of Medicine at Sulaiman, Al Rajhi University, Al Bukayriyah, Saudi Arabia.
Aladdin H ShadyabHerbert Wertheim School of Public Health and Human Longevity Science, University of California, San Diego, La Jolla, CA, USA.
Fred K TabungInternal Medicine, Division of Medical Oncology, The Ohio State University College of Medicine and Comprehensive Cancer Center, Columbus, OH, USA.
Xiaochen ZhangDivision of Epidemiology, College of Public Health, Comprehensive Cancer Center, Ohio State University, Columbus, OH, USA.
Jean Wactawski-WendeDepartment of Epidemiology and Environmental Health, School of Public Health, University of Buffalo, Buffalo, NY, USA.
Thomas E RohanDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY, 10461, USA. thomas.rohan@einsteinmed.org.
Albert Einstein College of Medicine · USThe Ohio State University · USSulaiman Al Rajhi Colleges · SAUniversity at Buffalo, State University of New York · USUniversity of Arizona · USUniversity of California, San Diego · USUniversity of Tennessee Health Science Center · US

Funding

Addressing Obesity to Reduce Cancer Risk and Health Disparities in Underserved PopulationsF99CA253745 · NCI · OHIO STATE UNIVERSITY · PI ZHANG, XIAOCHEN · 2020 to 2021
$86k
NCI NIH HHS F99 CA253745NHLBI NIH HHS HHSN268201600003CNHLBI NIH HHS HHSN268201600004CNHLBI NIH HHS HHSN268201600018C
6 · The paper itself

Abstract

purposeLifestyle factors such as smoking, alcohol, body weight, physical activity, and diet quality have been associated with the risk of pancreatic cancer. However, studies of their combined association in women are limited.

methodsData on smoking habits, alcohol intake, diet composition, recreational physical activity, body weight, and waist circumference, obtained at recruitment for 136,945 postmenopausal women (aged 50-79 years) participating in the Women's Health Initiative study, were categorized separately, with higher scores for each variable assigned to the categories representing healthier behaviors. The combined healthy lifestyle index (HLI) score, created by summing the scores for each risk factor, was grouped into quartiles. We used multivariable-adjusted Cox regression to estimate hazard ratios (HR) and 95% confidence intervals (CI) for pancreatic cancer risk in association with the HLI.

resultsOver an average follow-up period of approximately 16.0 years, 1,119 incident cases of pancreatic cancer were ascertained. Compared to women in the lowest HLI quartile, those in the upper quartiles (qt) had a reduced risk of pancreatic cancer (multivariable-adjusted HRqt

conclusionsOur findings suggest that in postmenopausal women, a healthy lifestyle is associated with reduced risk of pancreatic cancer.

Indexed as

Healthy LifestylePancreatic NeoplasmsBody Mass IndexBody WeightFemaleHumansProspective StudiesRisk FactorsWomen's HealthHealthy lifestyle indexPancreatic cancerPostmenopausal womenPropspective cohort study

Identifiers

PMID35235084
PMCPMC10286627
OpenAlexW4214940057

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.