ArticlePlant physiology2022
GmMDE genes bridge the maturity gene E1 and florigens in photoperiodic regulation of flowering in soybean.
Article in Plant physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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24 citing papers in PubMed, 43 citations in OpenAlex.
- GmMADS17, a MADS-box transcription factor, promotes flowering in soybean.BMC plant biology · 2026Article
- High-resolution quantitative trait loci mapping and pyramiding effects of candidate genes for plant height in soybean.The plant genome · 2026Article
- Glycine max Jumonji C domain-containing proteins JMJ19/20 exhibit endopeptidase activity and interact with LUXs to mediate flowering time.Nucleic acids research · 2026Article
- GViT-GP: injecting the genomic relationship matrix as an inductive bias into a vision transformer via cross-attention for genomic prediction.Frontiers in genetics · 2026Article
- CRISPR/Cas genome editing in soybean: challenges and new insights to overcome existing bottlenecks.Journal of advanced research · 2025Review
- Functional Genomics: From Soybean to Legume.International journal of molecular sciences · 2025Review
- TaFT-D1 positively regulates grain weight by acting as a coactivator of TaFDL2 in wheat.Plant biotechnology journal · 2025Article
- Exploring the multifaceted dynamics of flowering time regulation in field crops: Insight and intervention approaches.The plant genome · 2025Review
- Enhancing Agrobacterium-mediated soybean transformation efficiency with an auxiliary solution.Crop health · 2024Article
- Harnessing Multi-Omics Strategies and Bioinformatics Innovations for Advancing Soybean Improvement: A Comprehensive Review.Plants (Basel, Switzerland) · 2024Review
- A Novel 10-Base Pair Deletion in the First Exon ofInternational journal of molecular sciences · 2024Article
- Flowering time regulator qFT13-3 involved in soybean adaptation to high latitudes.Plant biotechnology journal · 2024Article
- Genome-wide association study reveals GmFulb as candidate gene for maturity time and reproductive length in soybeans (Glycine max).PloS one · 2024Article
- Integrated eQTL mapping approach reveals genomic regions regulating candidate genes of theFrontiers in plant science · 2024Article
- Genome-wide association study revealed some new candidate genes associated with flowering and maturity time of soybean in Central and West Siberian regions of Russia.Frontiers in plant science · 2024Article
- Insight from expression profiles ofFrontiers in plant science · 2024Review
- Unlocking Nature's Clock: CRISPR Technology in Flowering Time Engineering.Plants (Basel, Switzerland) · 2023Review
- PH13 improves soybean shade traits and enhances yield for high-density planting at high latitudes.Nature communications · 2023Article
- Molecular breeding for improvement of photothermal adaptability in soybean.Molecular breeding : new strategies in plant improvement · 2023Article
- GmEID1 modulates light signaling through the Evening Complex to control flowering time and yield in soybean.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
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Authors and funding
18 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Soybean (Glycine max) is highly sensitive to photoperiod, which affects flowering time and plant architecture and thus limits the distribution range of elite soybean cultivars. The major maturity gene E1 confers the most prominent effect on photoperiod sensitivity, but its downstream signaling pathway remains largely unknown. Here, we confirm that the encoded E1 protein is a transcriptional repressor. The expression of seven GmMDE genes (Glycine max MADS-box genes downregulated by E1) was suppressed when E1 was overexpressed and promoted when E1 was knocked out through clustered regularly-interspaced short palindromic repeats (CRISPR)/CRISPR associated protein 9 (Cas9)-mediated mutagenesis. These GmMDEs exhibited similar tissue specificity and expression patterns, including in response to photoperiod, E1 expression, and E1 genotype. E1 repressed GmMDE promoter activity. Results for two GmMDEs showed that E1 epigenetically silences their expression by directly binding to their promoters to increase H3K27me3 levels. The overexpression of GmMDE06 promoted flowering and post-flowering termination of stem growth. The late flowering phenotype of E1-overexpressing soybean lines was reversed by the overexpression of GmMDE06, placing GmMDE06 downstream of E1. The overexpression of GmMDE06 increased the expression of the soybean FLOWERING LOCUS T orthologs GmFT2a and GmFT5a, leading to feedback upregulation of GmMDE, indicating that GmMDE and GmFT2a/GmFT5a form a positive regulatory feedback loop promoting flowering. GmMDE06 also promoted post-flowering termination of stem growth by repressing the expression of the shoot identity gene Dt1. The E1-GmMDEs-GmFT2a/5a-Dt1 signaling pathway illustrates how soybean responds to photoperiod by modulating flowering time and post-flowering stem termination.
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