Evidence map›Paper›PMID 35234904›Full record

ArticleNucleic acids research2022

TransposonUltimate: software for transposon classification, annotation and detection.

Kevin Riehl, Cristian Riccio, Eric A Miska, Martin Hemberg

Abstract read
In one paragraph

Article in Nucleic acids research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed.

  1. T2T genomes ofGenome research · 2026
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  18. Conservative evolution of genetic and genomic features inbioRxiv : the preprint server for biology · 2025
    Article
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kevin RiehlGurdon Institute, University of Cambridge, Cambridge CB2 1QN, UK.
Cristian RiccioGurdon Institute, University of Cambridge, Cambridge CB2 1QN, UK.
Eric A MiskaGurdon Institute, University of Cambridge, Cambridge CB2 1QN, UK.
Martin HembergWellcome Sanger Institute, Wellcome Genome Campus, Hinxton CB10 1SA, UK.ORCID 0000-0001-8895-5239

Funding

Cancer Research UK 27826Cancer Research UK C13474/A18583Cancer Research UK C6946/A14492Wellcome TrustWellcome Trust 092096/Z/10/ZWellcome Trust 219475/Z/19/Z
6 · The paper itself

Abstract

Most genomes harbor a large number of transposons, and they play an important role in evolution and gene regulation. They are also of interest to clinicians as they are involved in several diseases, including cancer and neurodegeneration. Although several methods for transposon identification are available, they are often highly specialised towards specific tasks or classes of transposons, and they lack common standards such as a unified taxonomy scheme and output file format. We present TransposonUltimate, a powerful bundle of three modules for transposon classification, annotation, and detection of transposition events. TransposonUltimate comes as a Conda package under the GPL-3.0 licence, is well documented and it is easy to install through https://github.com/DerKevinRiehl/TransposonUltimate. We benchmark the classification module on the large TransposonDB covering 891,051 sequences to demonstrate that it outperforms the currently best existing solutions. The annotation and detection modules combine sixteen existing softwares, and we illustrate its use by annotating Caenorhabditis elegans, Rhizophagus irregularis and Oryza sativa subs. japonica genomes. Finally, we use the detection module to discover 29 554 transposition events in the genomes of 20 wild type strains of C. elegans. Databases, assemblies, annotations and further findings can be downloaded from (https://doi.org/10.5281/zenodo.5518085).

Indexed as

DNA Transposable ElementsSoftwareAnimalsBenchmarkingCaenorhabditis elegansFungiGenomeMolecular Sequence AnnotationOryzaReference StandardsDNA Transposable Elements

Identifiers

PMID35234904
PMCPMC9226531

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.