ArticleJournal of aging and health2022
Loneliness, Social Isolation, and All-Cause Mortality in a Large Sample of Older Adults.
Article in Journal of aging and health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Loneliness, social isolation, and living alone: a comprehensive systematic review, meta-analysis, and meta-regression of mortality risks in older adults.Aging clinical and experimental research · 2025Pooled it
- A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality.Nature human behaviour · 2023Pooled it
- Comparing Perceptions of Technology-Based Interactions Among Depressed Older Adults Participating in a Randomized Controlled Trial During the COVID-19 Pandemic.Journal of general internal medicine · 2026Trial
- Associations of Social and Physical Isolation With Material Deprivation and Inadequate Use of Preventive Care in the United States.Annals of family medicine · 2026Article
- Loneliness and cognitive decline among U.S. adults: A stratified analysis of the BRFSS.PloS one · 2026Article
- Effects of social isolation on all-cause mortality in older adults: do age, gender, and measurement matter?Innovation in aging · 2026Article
- Loneliness and all-cause mortality in the United States.PloS one · 2026Article
- Observational
- Mammography Screening Among Women Living With HIV in the United States: A Quantitative Analysis of the Role of Health Care Empowerment.The Journal of the Association of Nurses in AIDS Care : JANAC · 2025Article
- Large floods drive changes in cause-specific mortality in the United States.Nature medicine · 2025Article
- Loneliness, Social Isolation, and Digital Health Literacy Among Older Women Living Alone in South Korea During the COVID-19 Pandemic.Psychiatry investigation · 2025Article
- Mortality burden attributable to long-term exposure to fine particulate matter among older adults in Korea.Epidemiology and health · 2025Article
- The impact of bidirectional emotional support on social isolation in older adults: the mediating role of depression and the moderating role of activities of daily living.Frontiers in public health · 2025Article
- Association of memory function with COVID-19 outcomes in adults aged 50 years and older: analysis of three prospective cohorts.Frontiers in public health · 2025Article
- Association of Social Isolation and Loneliness With Chronic Low Back Pain Among Older Adults: A Cross-sectional Study From Japan Gerontological Evaluation Study (JAGES).Journal of epidemiology · 2024Article
- The Association Between Community Dialogue and Loneliness in Rural Japanese Communities: A Cross-Sectional Study.Cureus · 2024Article
- The unique and synergistic effects of social isolation and loneliness on 20-years mortality risks in older men and women.Frontiers in public health · 2024Article
- Long-term care need, loneliness, and perceived social isolation during the COVID-19 pandemic: evidence from the German Ageing Survey.Aging clinical and experimental research · 2023Article
- Recruiting Socially Disconnected Latinos Caring for a Person with Alzheimer's Disease and Related Dementias During the COVID-19 Pandemic: Lessons Learned.Clinical gerontologist · 2023Article
- COVID-19 anxiety: The impact of older adults' transmission of negative information and online social networks.Aging and health research · 2023Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesUsing data from a large random sample of U.S. older adults (
methodsThe UCLA-3 Loneliness Scale and the Social Network Index (SNI) were used to define loneliness and social isolation. Cox proportional hazards regression models were performed.
resultsAmong study participants, there were 548 deaths. In separate, adjusted models, loneliness (severe and moderate) and social isolation (limited and moderate social network) were both associated with all-cause mortality. When modeled together, social isolation (limited and moderate social network) along with severe loneliness remained significantly associated with mortality. DISCUSSION: Results demonstrate that both loneliness and social isolation contribute to greater risk of mortality within our population of older adults. As the COVID-19 pandemic continues, loneliness and social isolation should be targeted safely in efforts to reduce mortality risk among older adults.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.