Evidence map›Paper›PMID 35234536›Full record

SynthesisEnvironmental health perspectives2022

Exposure to Outdoor Particulate Matter Air Pollution and Risk of Gastrointestinal Cancers in Adults: A Systematic Review and Meta-Analysis of Epidemiologic Evidence.

Natalie Pritchett, Emily C Spangler, George M Gray, Alicia A Livinski, Joshua N Sampson, Sanford M Dawsey, Rena R Jones

Open access · diamondAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Environmental health perspectives, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 9 pooled it
12.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 9 syntheses or guidelines pooled it, 122 citations in OpenAlex.

  1. Impact of Pollution on Cancer: A Systematic Review and Meta-Analysis with Focus on Air Pollution.International journal of environmental research and public health · 2026
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  8. Effect of Fine Particulate Matter Exposure on Liver Enzymes: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2023
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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Natalie PritchettNational Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.ORCID 0000-0002-1222-4808
Emily C SpanglerGlobal Health Section, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-1310-770X
George M GrayDepartment of Environmental and Occupational Health, Milken Institute School of Public Health, George Washington University, Washington DC, USA.ORCID 0000-0001-9995-7889
Alicia A LivinskiNational Institutes of Health Library, Office of Research Services, National Institutes of Health, Bethesda, Maryland, USA.ORCID 0000-0002-7201-3500
Joshua N SampsonNational Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
Sanford M DawseyNational Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.ORCID 0000-0003-2185-0533
Rena R JonesNational Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.ORCID 0000-0003-1294-1679
National Institutes of Health · USMilken Institute · USUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOutdoor air pollution is a known lung carcinogen, but research investigating the association between particulate matter (PM) and gastrointestinal (GI) cancers is limited.

objectivesWe sought to review the epidemiologic literature on outdoor PM and GI cancers and to put the body of studies into context regarding potential for bias and overall strength of evidence.

methodsWe conducted a systematic review and meta-analysis of epidemiologic studies that evaluated the association of fine PM [PM with an aerodynamic diameter of

resultsTwenty studies met inclusion criteria and included participants from 14 countries; nearly all were of cohort design. All studies identified positive associations between PM exposure and risk of at least one GI cancer, although in 3 studies these relationships were not statistically significant. Three of 5 studies estimated associations with

conclusionWe concluded there is some evidence of associations between

Indexed as

Air PollutantsAir PollutionGastrointestinal NeoplasmsAdultEnvironmental ExposureHumansParticulate MatterAir PollutantsParticulate Matter

Identifiers

PMID35234536
PMCPMC8890324
OpenAlexW4214827546

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.