Evidence map›Paper›PMID 35234514›Full record

ArticleMicrobiology spectrum2022

Rapid Bacterial Detection in Urine Using Laser Scattering and Deep Learning Analysis.

Kwang Seob Lee, Hyung Jae Lim, Kyungnam Kim, Yeon-Gyeong Park, Jae-Woo Yoo, Dongeun Yong

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kwang Seob Lee *Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, South Korea.ORCID 0000-0002-6286-108X
Hyung Jae Lim *Department of Research and Development, The Wave Talk, Inc., Daejeon, South Korea.
Kyungnam KimResearch Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, South Korea.
Yeon-Gyeong ParkDepartment of Research and Development, The Wave Talk, Inc., Daejeon, South Korea.
Jae-Woo YooDepartment of Research and Development, The Wave Talk, Inc., Daejeon, South Korea.
Dongeun YongDepartment of Laboratory Medicine, Yonsei University College of Medicine, Seoul, South Korea.
Yonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Images of laser scattering patterns generated by bacteria in urine are promising resources for deep learning. However, floating bacteria in urine produce dynamic scattering patterns and require deep learning of spatial and temporal features. We hypothesized that bacteria with variable bacterial densities and different Gram staining reactions would generate different speckle images. After deep learning of speckle patterns generated by various densities of bacteria in artificial urine, we validated the model in an independent set of clinical urine samples in a tertiary hospital. Even at a low bacterial density cutoff (1,000 CFU/mL), the model achieved a predictive accuracy of 90.9% for positive urine culture. At a cutoff of 50,000 CFU/mL, it showed a better accuracy of 98.5%. The model achieved satisfactory accuracy at both cutoff levels for predicting the Gram staining reaction. Considering only 30 min of analysis, our method appears as a new screening tool for predicting the presence of bacteria before urine culture.

Indexed as

Deep LearningUrinary Tract InfectionsBacteriaFemaleHumansLasersMaleUrinalysisdeep learninglaser scatterpredictionrapid testsurinary tract infection

Identifiers

PMID35234514
PMCPMC8941854
OpenAlexW4214927878

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.