Evidence map›Paper›PMID 35234500›Full record

ArticleMicrobiology spectrum2022

All Driven by Energy Demand? Integrative Comparison of Metabolism of Enterococcus faecalis Wildtype and a Glutamine Synthase Mutant.

Seyed Babak Loghmani, Eric Zitzow, Gene Ching Chiek Koh, Andreas Ulmer, Nadine Veith, Ruth Großeholz, Madlen Rossnagel, Maren Loesch, Ruedi Aebersold, Bernd Kreikemeyer and 2 more

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Seyed Babak LoghmaniDepartment of Modelling of Biological Processes, BioQuant/COS Heidelberg, Heidelberg Universitygrid.7700.0, Heidelberg, Germany.
Eric ZitzowInstitute for Medical Microbiology, Virology and Hygiene, Rostock University Medical Centre, Rostock, Germany.
Gene Ching Chiek KohDepartment of Biology, Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland.
Andreas UlmerInstitute of Biochemical Engineering, University of Stuttgart, Stuttgart, Germany.
Nadine VeithDepartment of Modelling of Biological Processes, BioQuant/COS Heidelberg, Heidelberg Universitygrid.7700.0, Heidelberg, Germany.
Ruth GroßeholzDepartment of Modelling of Biological Processes, BioQuant/COS Heidelberg, Heidelberg Universitygrid.7700.0, Heidelberg, Germany.
Madlen RossnagelInstitute for Medical Microbiology, Virology and Hygiene, Rostock University Medical Centre, Rostock, Germany.
Maren LoeschInstitute of Biochemical Engineering, University of Stuttgart, Stuttgart, Germany.
Ruedi AebersoldDepartment of Biology, Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland.ORCID 0000-0002-9576-3267
Bernd KreikemeyerInstitute for Medical Microbiology, Virology and Hygiene, Rostock University Medical Centre, Rostock, Germany.ORCID 0000-0001-9527-5098
Tomas FiedlerInstitute for Medical Microbiology, Virology and Hygiene, Rostock University Medical Centre, Rostock, Germany.
Ursula KummerDepartment of Modelling of Biological Processes, BioQuant/COS Heidelberg, Heidelberg Universitygrid.7700.0, Heidelberg, Germany.ORCID 0000-0002-6413-2382
Heidelberg University · DEUniversity of Rostock · DEETH Zurich · CHUniversity of Stuttgart · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lactic acid bacteria (LAB) play a significant role in biotechnology, e.g., food industry and also in human health. Many LAB genera have developed a multidrug resistance in the past few years, causing a serious problem in controlling hospital germs worldwide. Enterococcus faecalis accounts for a large part of the human infections caused by LABs. Therefore, studying its adaptive metabolism under various environmental conditions is particularly important to promote the development of new therapeutic approaches. In this study, we investigated the effect of glutamine auxotrophy (Δ

Indexed as

Enterococcus faecalisGlutamate-Ammonia LigaseGlutamineHumansProteomeProteomicsGlutamate-Ammonia LigaseGlutamineProteomeEnterococcus faecalisglutamine synthase mutantpH adaptation

Identifiers

PMID35234500
PMCPMC8941932
OpenAlexW4226160369

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.