Evidence map›Paper›PMID 35233701›Full record

ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2022

Changes in Distensibility Index During an Incremental POEM Myotomy.

Tom B Knowles, Anee Sophia Jackson, Shu-Ching Chang, Drew B Schembre, Alexander S Farivar, Ralph W Aye, Brian E Louie

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In one paragraph

Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Tom B KnowlesDivision of Thoracic Surgery, Swedish Digestive Health Institute and Medical Center, Suite 900, 1101 Madison Street, Seattle, WA, 98104, USA.
Anee Sophia JacksonDivision of Thoracic Surgery, Swedish Digestive Health Institute and Medical Center, Suite 900, 1101 Madison Street, Seattle, WA, 98104, USA.
Shu-Ching ChangMedical Data Research Center, Providence St. Joseph Health, Portland, OR, USA.
Drew B SchembreDivision of Gastroenterology, John Muir Health, Walnut Creek, CA, USA.
Alexander S FarivarDivision of Thoracic Surgery, Swedish Digestive Health Institute and Medical Center, Suite 900, 1101 Madison Street, Seattle, WA, 98104, USA.
Ralph W AyeDivision of Thoracic Surgery, Swedish Digestive Health Institute and Medical Center, Suite 900, 1101 Madison Street, Seattle, WA, 98104, USA.
Brian E LouieDivision of Thoracic Surgery, Swedish Digestive Health Institute and Medical Center, Suite 900, 1101 Madison Street, Seattle, WA, 98104, USA. brian.louie@swedish.org.ORCID http://orcid.org/0000-0002-7599-1000
Swedish Medical Center · USJohn Muir Health · USProvidence College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA longer myotomy for the treatment of achalasia is associated with worse gastroesophageal reflux disease despite palliating dysphagia. Recently, clinical outcomes have been correlated to the distensibility of the distal esophagus, which is measured intra-operatively using an endoscopic functional luminal image probe (EndoFLIP). We aimed to determine the minimum per oral endoscopic myotomy (POEM) length to allow for adequate distensibility index (DI).

methodsA 6-cm myotomy conducted in 2-cm increments during POEM was performed for patients with achalasia I and II from 2017 to 2019. The EndoFLIP was used to measure the DI intra-operatively: (1) prior to intervention, (2) following creation of the submucosal tunnel, (3) following transection of the high-pressure zone (HPZ), (4) following the distal extension, and (5) following the proximal esophageal extension.

resultsA total of 16 patients underwent POEM. Ages ranged from 21 to 78 years, 10 were male, and 13 had type II achalasia. The median DI was 2.7 (1.4-3.6) mm

conclusionsDistensibility changed with each myotomy increment and fell within the target range for most patients following a 2-4-cm myotomy. This suggests that a shorter myotomy may be appropriate for select patients, and the use of the EndoFLIP intra-operatively may allow for a tailored myotomy length.

Indexed as

Deglutition DisordersEsophageal AchalasiaMyotomyNatural Orifice Endoscopic SurgeryAdultAgedEsophageal Sphincter, LowerEsophagoscopyFemaleHumansMaleMiddle AgedTreatment OutcomeYoung AdultAchalasiaDistensibility indexEndoFLIPEndoscopyEsophagusMyotomyPOEM

Identifiers

PMID35233701
OpenAlexW4214513100

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.