Evidence map›Paper›PMID 35233522›Full record

ArticleBrain communications2022

Regional amyloid correlates of cognitive performance in ageing and mild cognitive impairment.

Daniel A Stevens, Clifford I Workman, Hiroto Kuwabara, Meryl A Butters, Alena Savonenko, Najilla Nassery, Neda Gould, Michael Kraut, Jin Hui Joo, Jessica Kilgore and 6 more

Open access · goldAbstract read
In one paragraph

Article in Brain communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Integration of Genetic and Imaging Data for Alzheimer's Disease Diagnosis and Interpretation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  5. The role of autoantibodies in Alzheimer's disease: Pathogenetic connections or epiphenomena?Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Review
  6. Journal of ginseng research · 2025
    Review
  7. Article
  8. Article
  9. Amyloid PET predicts longitudinal functional and cognitive trajectories in a heterogeneous cohort.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  10. Frontiers in aging neuroscience · 2025
    Article
  11. Intermittent supplementation withFrontiers in aging neuroscience · 2025
    Article
  12. Article
  13. Article
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Daniel A StevensDivision of Geriatric Psychiatry and Neuropsychiatry, Department of Psychiatry and Behavioral Sciences, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.ORCID https://orcid.org/0000-0002-7076-794X
Clifford I WorkmanDivision of Geriatric Psychiatry and Neuropsychiatry, Department of Psychiatry and Behavioral Sciences, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.ORCID https://orcid.org/0000-0002-2206-0325
Hiroto KuwabaraDivision of Nuclear Medicine and Molecular Imaging, Russell H. Morgan Department of Radiology and Radiological Sciences, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Meryl A ButtersDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Alena SavonenkoDepartment of Pathology (Neuropathology), School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Najilla NasseryDepartment of General Internal Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Neda GouldDivision of Geriatric Psychiatry and Neuropsychiatry, Department of Psychiatry and Behavioral Sciences, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Michael KrautDivision of Neuroradiology, Russell H. Morgan Department of Radiology and Radiological Sciences, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Jin Hui JooDivision of Geriatric Psychiatry and Neuropsychiatry, Department of Psychiatry and Behavioral Sciences, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Jessica KilgoreDivision of Geriatric Psychiatry and Neuropsychiatry, Department of Psychiatry and Behavioral Sciences, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Vidya KamathDivision of Geriatric Psychiatry and Neuropsychiatry, Department of Psychiatry and Behavioral Sciences, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Daniel P HoltDivision of Nuclear Medicine and Molecular Imaging, Russell H. Morgan Department of Radiology and Radiological Sciences, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Robert F DannalsDivision of Nuclear Medicine and Molecular Imaging, Russell H. Morgan Department of Radiology and Radiological Sciences, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Ayon NandiDivision of Nuclear Medicine and Molecular Imaging, Russell H. Morgan Department of Radiology and Radiological Sciences, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Chiadi U OnyikeDivision of Geriatric Psychiatry and Neuropsychiatry, Department of Psychiatry and Behavioral Sciences, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Gwenn S SmithDivision of Geriatric Psychiatry and Neuropsychiatry, Department of Psychiatry and Behavioral Sciences, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Johns Hopkins University · USUniversity of Pittsburgh · US

Funding

Research Education ComponentP30AG066507 · NIA · JOHNS HOPKINS UNIVERSITY · PI MARILYN S. ALBERT · 2020 to 2026
$29.3M
INTERDISCIPLINARY TRAINING PROGRAM IN NEUROSCIENCEST32MH015330 · NIMH · JOHNS HOPKINS UNIVERSITY · PI MARGOLIS, RUSSELL L · 1985 to 2024
$6.2M
Longitudinal Molecular Imaging of Neuropathology and Serotonin in Mild Cognitive ImpairmentR01AG059390 · NIA · JOHNS HOPKINS UNIVERSITY · PI SMITH, GWENN S · 2018 to 2022
$4.8M
NIA NIH HHS P30 AG066507NIA NIH HHS R01 AG059390NIMH NIH HHS T32 MH015330
6 · The paper itself

Abstract

Beta-amyloid deposition is one of the earliest pathological markers associated with Alzheimer's disease. Mild cognitive impairment in the setting of beta-amyloid deposition is considered to represent a preclinical manifestation of Alzheimer's disease.

Indexed as

ageingamyloidcognitionmild cognitive impairmentpositron-emission tomography

Identifiers

PMID35233522
PMCPMC8882008
OpenAlexW4210275659

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.